2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D1711
    MHI-148
    		98.39%
    MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells.
    MHI-148
  • HY-150086
    Copper Fluor-4
    		98.44%
    Copper Fluor-4 (CF4) is a Cu+-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10−13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission).
    Copper Fluor-4
  • HY-148263
    Biotin-PEG-Thiol (MW 2000)
    		≥98.0%
    Biotin-PEG-Thiol (MW 2000) is an active compound. Biotin-PEG-Thiol (MW 2000) is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG-Thiol (MW 2000) can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG-Thiol (MW 2000) is widely used in the research of agent release and nano new materials.
    Biotin-PEG-Thiol (MW 2000)
  • HY-D1834
    Vari Fluor 640 TSA（200×）
    Vari Fluor 640 TSA（200×） (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity.
    Vari Fluor 640 TSA（200×）
  • HY-136865
    MeOSuc-AAPV-AMC
    		98.07%
    MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm).
    MeOSuc-AAPV-AMC
  • HY-D1117
    NADA-green
    NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation.
    NADA-green
  • HY-D1835
    Vari Fluor 594 TSA（200×）
    Vari Fluor 594 TSA（200×） (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity.
    Vari Fluor 594 TSA（200×）
  • HY-D0893
    NSP-SA-NHS
    		99.72%
    NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed.
    NSP-SA-NHS
  • HY-D0965
    Procion Blue HB
    Procion Blue HB (Reactive Blue 2) is a purinergic antagonist.
    Procion Blue HB
  • HY-P0019
    Z-Gly-Gly-Arg-AMC
    		99.90%
    Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm).
    Z-Gly-Gly-Arg-AMC
  • HY-W400925
    Sulfo-Cy5-N3
    		99.12%
    Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-Cy5-N3
  • HY-D0193
    Ponceau 4R
    		99.84%
    Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids.
    Ponceau 4R
  • HY-W040230
    Acrylodan
    Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys34.
    Acrylodan
  • HY-D1425
    DCVJ
    		99.48%
    DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm).
    DCVJ
  • HY-D0826
    Cy2-SE (iodine)
    		98.11%
    Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Cy2-SE (iodine)
  • HY-D1567
    Cy7.5 NHS ester
    Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study.
    Cy7.5 NHS ester
  • HY-D0961
    Gallocyanine chloride
    Gallocyanine chloride is a synthetic blue dyestuff that can be used as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies. Gallocyanine chloride inhibits DKK1/LRP6 interaction (IC50=6.38 μM), activates Wnt signaling pathway, and causes β-catenin accumulation. Gallocyanine chloride exhibits anti-metastasis, anti-inflammatory and anti-fibrosis activities. Gallocyanine chloride can be used as a fluorescent probe for detection of superoxide anion radicals.
    Gallocyanine chloride
  • HY-103469
    Peroxy Orange 1
    		99.20%
    Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye.
    Peroxy Orange 1
  • HY-D2316
    Flipper-TR probe
    Flipper-TR probe (Compound FliptR probe) is a fluorescent probe specifically designed to measure cell membrane tension. Flipper-TR probe reports changes in membrane tension through variations in its fluorescence lifetime. Flipper-TR probe is applicable to a wide range of organisms including bacteria, yeast, mammals, and plants.
    Flipper-TR probe
  • HY-132969
    SBP-3264
    		98.50%
    SBP-3264 is a valuable chemical probe for understanding the roles of STK3 and STK4 in acute myeloid leukemia (AML).
    SBP-3264
Cat. No. Product Name / Synonyms Application Reactivity