2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-115692
    2-Coumaranone-1-L
    2-Coumaranone-1-L serves as a chemiluminescent probe. Under alkaline conditions and in the presence of oxygen, 2-Coumaranone-1-L is capable of undergoing chemiluminescence, which enables its application as a chemiluminescent substrate in biochemical assays. 2-Coumaranone-1-L exhibits its maximum emission wavelength at 442 nm. 2-Coumaranone-1-L is utilized in research within the realm of bioanalysis.
    2-Coumaranone-1-L
  • HY-D2201
    Fluorescent ACKR3 antagonist 1
    Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist.
    Fluorescent ACKR3 antagonist 1
  • HY-DY1073
    MitoPerOx (solution)
    MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction).
    Solution Concentration: 2 mM
    MitoPerOx (solution)
  • HY-D3007
    LD-CK
    LD-CK is a fluorescent probe based on a coumarin-chromone structure, specifically designed to visualize lipid droplet polarity changes and endowed with multimodal imaging capability. LD-CK contains a high-performance lipophilic coumarin moiety, which enables it to specifically target lipid droplets upon cellular entry while minimizing background fluorescence to the greatest extent. LD-CK has an excitation wavelength (Ex) of 488 nm and an emission wavelength (Em) of 540 nm (in low-polarity environments such as toluene) or 640 nm (in high-polarity environments such as glycerol), with its emission peak undergoing a redshift as solvent polarity increases.
    LD-CK
  • HY-D1321
    Cy 5 amine hydrochloride
    Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm).
    Cy 5 amine hydrochloride
  • HY-D1853
    Sulfo-Cy5 carboxylic acid
    Sulfo-Cy5 carboxylic acid is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm).
    Sulfo-Cy5 carboxylic acid
  • HY-D1935
    ATTO 465 NHS ester
    ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
    ATTO 465 NHS ester
  • HY-D0425
    C.I. Direct red 84
    C.I. Direct red 84 is a good dyeing agent for cotton fabrics.
    C.I. Direct red 84
  • HY-NP164E
    Concanavalin A-AF430
    Concanavalin A-AF430 (Con A-AF430) is an AF430-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins.
    Concanavalin A-AF430
  • HY-D1128
    Disperse red 151
    Disperse red 151 is a red dye derived from anthraquinone. It is used in plastics, textiles and cosmetics.
    Disperse red 151
  • HY-D2090
    PE-VF620 Maleimide
    PE-VF620 Maleimide is a fluorescent dye.
    PE-VF620 Maleimide
  • HY-D2239
    Sulfo-Cy3.5 maleimide
    Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm.
    Sulfo-Cy3.5 maleimide
  • HY-D0130
    Xanthamide 8
    Xanthamide 8 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Xanthamide 8
  • HY-116455
    BRD-9526
    BRD-9526 is a potent and selective Sonic Hedgehog (Shh) pathway inhibitor with potential anti-cancer activity. The mechanism of BRD-9526 is similar in some ways to commonly used inhibitors such as cyclopamine, but is significantly different in other ways. The discovery of BRD-9526 may provide a useful probe for studying complex signaling pathways.
    BRD-9526
  • HY-D2072
    ATTO 680 carboxy
    ATTO 680 carboxy is a carboxyl derivative of ATTO 680, the maximum excitation/emission wavelength is: 681/698 nm.
    ATTO 680 carboxy
  • HY-D1073
    DiOC7(3)
    DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.
    DiOC7(3)
  • HY-D2836H
    FITC-HA (MW 7000)
    FITC-HA (FITC-Hyaluronate) (MW 7000) is a fluorescent dye composed of FITC (HY-66019) and Hyaluronic acid (HY-B0633A) (HA). FITC-HA (FITC-Hyaluronate) (MW 7000) can be used for cell tracing and drug delivery.
    FITC-HA (MW 7000)
  • HY-D1946
    ATTO 590 alkyne
    ATTO 590 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 alkyne is an alkyne derivative of ATTO 590 and can be used to label proteins or antibodies.
    ATTO 590 alkyne
  • HY-W271064
    1-Methylpyrene
    		99.51%
    1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
    1-Methylpyrene
  • HY-173538
    C6 NBD Sphingomyelin (d18:1/6:0)
    C6 NBD Sphingomyelin (d18:1/6:0) (NBD SM(d18:1/6:0)) is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). C6 NBD Sphingomyelin (d18:1/6:0) has neutral sphingomyelinase (N-SMase) activity.
    C6 NBD Sphingomyelin (d18:1/6:0)
Cat. No. Product Name / Synonyms Application Reactivity