2. Signaling Pathways
  3. Immunology/Inflammation
  4. FAP
  5. FAP Substrate

FAP Substrate

FAP Substrates (2):

Cat. No. Product Name Effect Purity
  • HY-160289
    ARI-3144
    		Substrate 99.72%
    ARI-3144 is an excellent and specific substrate for fibroblast activation protein (FAP). ARI-3144 is usually coupled with the fluorophore 7-Amino-4-methylcoumarin (HY-D0027) (AMC) for detection and quantification of FAP.
  • HY-177083
    Faridoxorubicin
    		Substrate
    Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα). Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis).