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Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (209):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129764A
    (17E)-Prostaglandin F3α
    (17E)-Prostaglandin F3α (17-trans-PGF3α) is a double bond isomer of Prostaglandin F3α (HY-129764) and a potential metabolite of trans dietary fatty acids. (17E)-Prostaglandin F3α has anti-inflammatory activity.
    (17E)-Prostaglandin F3α
  • HY-15743A
    (R)-Birabresib
    		99.94%
    (R)-Birabresib is the isomer of Birabresib (HY-15743), and can be used as an experimental control. Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM.
    (R)-Birabresib
  • HY-135597
    N-Acetyl-5-methyl-L-tryptophan
    		98.39%
    N-Acetyl-5-methyl-L-tryptophan is a N-Acetyl-L-tryptophan analog.
    N-Acetyl-5-methyl-L-tryptophan
  • HY-161474
    Antiproliferative agent-50
    Antiproliferative agent-50 (Compd VIII-a) is an inhibitor of myeloma cell proliferation and may be used to inhibit multiple myeloma.
    Antiproliferative agent-50
  • HY-141551B
    (R)-GNE-274
    (R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader).
    (R)-GNE-274
  • HY-149053A
    (S)-OY-101
    (S)-OY-101 is an isomer of OY-101 (HY-149053).
    (S)-OY-101
  • HY-W699829
    (3R,5R)-Rosuvastatin Lactone-d6
    (3R,5R)-Rosuvastatin Lactone-d6 is the deuterium labeled (3R,5R)-Rosuvastatin Lactone (HY-135406). (3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone.
    (3R,5R)-Rosuvastatin Lactone-d<sub>6</sub>
  • HY-107608A
    5(S),12(S)-Leukotriene B4
    5(S),12(S)-Leukotriene B4 (5(S),12(S)-LTB4; 5(S),12(S)-DiHETE) is a stereochemical isomer of LTB4 (HY-107608).
    5(S),12(S)-Leukotriene B4
  • HY-124281A
    9(S)-PAHSA
    9(S)-PAHSA is a S-enantiomer of 9-PAHSA. 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation.
    9(S)-PAHSA
  • HY-N7801
    (±)5-HEPE
    (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.
    (±)5-HEPE
  • HY-115408
    9(R)-HETE
    9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE. At a concentration of 300 nM, 9(R)-HETE activates RXRγ-dependent transcription 1.5 fold relative to a control.1 Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results.
    9(R)-HETE
  • HY-W747563
    11-trans Leukotriene D4
    11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
    11-trans Leukotriene D4
  • HY-B0317DR
    (R)-Amlodipine (Standard)
    (R)-Amlodipine (Standard) is the analytical standard of (R)-Amlodipine. This product is intended for research and analytical applications. (R)-Amlodipine is the R-Enantiomer of Amlodipine (HY-B0317 )
    (R)-Amlodipine (Standard)
  • HY-W726667A
    (R)-(-)-Citramalic acid lithium
    (R)-(-)-Citramalic acid ((R)-Citramalate) lithium, a lithium salt of Citramalic acid, is the R enantiomer of Citramalic acid lithium. (R)-(-)-Citramalic acid lithium is involved in the metabolism of glutamate through the methylaspartate pathway. (R)-(-)-Citramalic acid lithium is promising for research of neurological disorders.
    (R)-(-)-Citramalic acid lithium
  • HY-155953
    6-epi-COTC
    6-epi-COTC is a diastereoisomer of Streptomyces metabolite with a anti-cancer activitie.
    6-epi-COTC
  • HY-19471
    (rac)-ZK-304709
    (rac)-ZK-304709 is an isoform of ZK-304709 and is an orally active multi-targeted tumor growth inhibitor that inhibits multiple cell cycle-dependent kinases (CDKs), vascular endothelial growth factor receptor kinases (VEGF-RTKs), and platelet-derived growth factor receptor kinase β (PDGF-RTKβ). (rac)-ZK-304709 can dose-dependently inhibit the proliferation and colony formation of neuroendocrine tumor (NET) cells. (rac)-ZK-304709 directly acts on NET cells by inducing G2 cell cycle arrest and apoptosis, while reducing the expression of MCL1, survivin, and HIF1α. (rac)-ZK-304709 effectively controls tumor growth by inducing apoptosis and inhibiting tumor-induced angiogenesis, and may become a potential agent for inhibiting NET.
    (rac)-ZK-304709
  • HY-106841A
    (S)-Draflazine
    (S)-Draflazine ((-)-Draflazine) is the (S)-configuration of Draflazine (HY-106841). (S)-Draflazine is a potent blocker of nucleoside transport.
    (S)-Draflazine
  • HY-133022R
    trans-2-Undecenoic acid (Standard)
    trans-2-Undecenoic acid (Standard) is the analytical standard of trans-2-Undecenoic acid. This product is intended for research and analytical applications. trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O[1].
    trans-2-Undecenoic acid (Standard)
  • HY-156717
    RE-33
    RE-33 is an analgesic compound. RE-33 has blood brain barrier penetration ability.
    RE-33
  • HY-W740803
    15-cis-Phytofluene
    15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis.
    15-cis-Phytofluene