2. Signaling Pathways
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  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (217):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-50707
    (Rac)-TTA-P2
    		98.69%
    (Rac)-TTA-P2 is the isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease.
    (Rac)-TTA-P2
  • HY-77111
    cis-INCB3344
    cis-INCB3344 is the isomer of INCB3344 (HY-50674), and can be used as an experimental control. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
    cis-INCB3344
  • HY-110155A
    (Rac)-LM11A-31 dihydrochloride
    		98.0%
    (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist.
    (Rac)-LM11A-31 dihydrochloride
  • HY-P10474
    RYTVELA
    		98.89%
    RYTVELA is a deriviative of the peptide antagonist of interleukin-1 receptor 1 (IL-1R1) d-(RYTVELA) (HY-P10353) that contains all L-amino acids.
    RYTVELA
  • HY-112101
    Prohydrojasmon racemate
    		≥98.0%
    Prohydrojasmon racemate (n-Propyl dihydrojasmonate) is the racemate of Prohydrojasmon. Prohydrojasmon is a synthesized plant growth regulator.
    Prohydrojasmon racemate
  • HY-19489
    (±)-Levomepromazine
    		99.88%
    (±)-Levomepromazine is the racemate of Levomepromazine. Levomepromazine is an orally active and potent antipsychotic agent.
    (±)-Levomepromazine
  • HY-132809B
    (Rac)-Baxdrostat
    		Inhibitor 99.03%
    (Rac)-Baxdrostat is the isomer of Baxdrostat (HY-132809), and can be used as an experimental control. Baxdrostat is a aldosterone synthase inhibitor.
    (Rac)-Baxdrostat
  • HY-12567A
    (R)-ML375
    		98.19%
    (R)-ML375 ((R)-VU0483253) is an enantiomer of ML375 (HY-12567). (R)-ML375 is devoid of M5 mAChR activity (hM5, IC50>30 μM).
    (R)-ML375
  • HY-W236273
    (E)-Ethyl cinnamate
    (E)-Ethyl cinnamate can be isolated from davana oil.
    (E)-Ethyl cinnamate
  • HY-N1952A
    cis-Isoeugenol
    cis-Isoeugenol is the cis isomer of Isoeugenol (HY-N1952).
    cis-Isoeugenol
  • HY-W342979
    Petroselaidic acid
    		≥98.0%
    Petroselaidic acid is a trans fatty acid and the trans isomer of Petroselinic acid (HY-113362). Petroselaidic acid can be found in dairy products such as cow's milk and goat's milk.
    Petroselaidic acid
  • HY-104065A
    (Rac)-Pyrotinib
    		99.29%
    (Rac)-Pyrotinib ((Rac)-SHR-1258) is the racemic form of Pyrotinib (HY-104065). Pyrotinib is a potent and selective dual EGFR/HER2 receptor inhibitor.
    (Rac)-Pyrotinib
  • HY-114395A
    (R)-NVS-ZP7-4
    		98.80%
    (R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway.
    (R)-NVS-ZP7-4
  • HY-111191A
    (R)-ONO-2952
    		99.81%
    (R)-ONO-2952 is a R-enantiomer of ONO-2952. ONO-2952 is a potent, selective and orally active TSPO antagonist with Kis of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes.
    (R)-ONO-2952
  • HY-160144S2
    (rac)-Lomedeucitinib
    		98.11%
    (rac)-Lomedeucitinib ((rac)-BMS-986322) is the racemate of Lomedeucitinib. Lomedeucitinib (BMS-986322) is a tyrosine protein kinase (TYK2) inhibitor. Lomedeucitinib has anti-inflammatory activity and significant inhibitory effect on IFNα (IC50=0.047 μM) production downstream of IL-12/TYK2. Lomedeucitinib is indicated for the study of plaque psoriasis and pruritus.
    (rac)-Lomedeucitinib
  • HY-13250B
    Silvestrol aglycone (enantiomer)
    		99.10%
    Silvestrol aglycone enantiomer is a cyclopenta benzofuran core phenol.
    Silvestrol aglycone (enantiomer)
  • HY-125135
    (-)-β-Peltatin
    		99.45%
    (-)-β-Peltatin is an organic heterotetracyclic compound with antitumor activity and phytometabolite effects that are functionally related to α-peltatin.
    (-)-β-Peltatin
  • HY-N7199
    (Rac)-Hydnocarpin
    		Control
    (Rac)-Hydnocarpin is a flavonoid isolated from Hydnocarpus anthelminthica, and exhibits moderate cytotoxic on cancer cells.
    (Rac)-Hydnocarpin
  • HY-145388B
    AU-16235
    		Control 99.54%
    AU-16235 is an inactive epimer of AU-15330. AU-16235 has no effect on cancer cell survival and growth
    AU-16235
  • HY-107842
    (Z)-JIB-04
    		Control 99.42%
    (Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis.
    (Z)-JIB-04