2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y0004
    2-Pyridinemethanol
    		99.98%
    2-Pyridinemethanol is a pyridylalcohol, with hypoglycemic activity.
    2-Pyridinemethanol
  • HY-B0917
    Bromindione
    		98.11%
    Bromindione is a potent and long-acting, Inandione-derived, oral anticoagulant compound.
    Bromindione
  • HY-N8531
    4α-Methylcholesterol
    		99.90%
    4α-Methylcholesterol is a Cholesterol derivative. 4α-Methylcholesterol can oxidize 3-hydroxy steroid, with the apparent Km of 12.6 μM.
    4α-Methylcholesterol
  • HY-W279223
    Potassium tetrakis(4-chlorophenyl)borate
    		98.0%
    Potassium tetrakis(4-chlorophenyl)borate is an active compound.
    Potassium tetrakis(4-chlorophenyl)borate
  • HY-400882
    Tosylate-DPA-714
    Tosylate-DPA-714 (compound 2) is a DPA-714 (HY-122607) tosylate analog. Tosylate-DPA-714 is a precursor for 18F-DPA-714. DPA-714 is a translocator protein (TSPO)-specific ligand.
    Tosylate-DPA-714
  • HY-W004288
    Methyl myristate
    		99.70%
    Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl myristate
  • HY-W087207
    Loxoprofen L-menthol ester
    		99.73%
    Loxoprofen L-menthol ester is a degradation product Loxoprofen sodium (HY-B0578A). Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties.
    Loxoprofen L-menthol ester
  • HY-19714
    XY1
    		99.10%
    XY1 is an analog of SGC707 (HY-19715), a potent and selective PRMT3 inhibitor with an IC50 of 31 nM. XY1 is completely inactive against PRMT3. XY1 and SGC707 represent an excellent pair of tools for further elucidating the biological functions and disease relevance of PRMT3.
    XY1
  • HY-34887
    Acridone-4-carboxylic acid
    		98.69%
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM.
    Acridone-4-carboxylic acid
  • HY-15792
    (R)-FL118
    		99.94%
    (R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity.
    (R)-FL118
  • HY-128856
    P7C3-OMe
    		98.26%
    P7C3-OMe is a pro-neurogenic compound, has therapeutic benefits in neuropsychiatric and/or neurodegenerative disease. The R-enantiomer of P7C3-OMe is far more active than the S-enantiomer.
    P7C3-OMe
  • HY-76779
    4-(Chloromethyl)-7-hydroxycoumarin
    		98.01%
    4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII.
    4-(Chloromethyl)-7-hydroxycoumarin
  • HY-12692
    DO3A tert-Butyl ester
    		98.0%
    DOTA tert-Butyl ester is a cyclic tosamide benzyl derivative.
    DO3A tert-Butyl ester
  • HY-139453
    LP-184
    		99.37%
    LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2).
    LP-184
  • HY-176462
    Gly-Dasatinib
    Gly-Dasatinib (compound I-7-1), an amino acid analog of Dasatinib (HY-10181), is a tyrosine kinase inhibitor. Gly-Dasatinib can be used for the study of cancer.
    Gly-Dasatinib
  • HY-W015449
    2-(2-Aminopropanamido)propanoic acid
    2-(2-Aminopropanamido)propanoic acid is an alanine derivative.
    2-(2-Aminopropanamido)propanoic acid
  • HY-159162A
    7-(2-Aminoethyl)camptothecin TFA
    		99.61%
    7-(2-Aminoethyl)camptothecin TFA (7CPT TFA) is the TFA salt form of Camptothecin (HY-16560) derivative 7-(2-Aminoethyl)camptothecin (HY-159162). 7-(2-Aminoethyl)camptothecin TFA can be used for synthesis of conjugate with triple helix-forming oligonucleotides (TFOs) and camptothecin (CPT). The TFO-CPT conjugate is used for DNA cleavage.
    7-(2-Aminoethyl)camptothecin TFA
  • HY-107835
    Flumethrin
    Flumethrin is an active compound.
    Flumethrin
  • HY-130702
    24(28)-Dehydroergosterol
    24(28)-Dehydroergosterol is a derivative of Episterol. Episterol is a sterol involved in the biosynthesis of steroids.
    24(28)-Dehydroergosterol
  • HY-P2023
    Hirugen
    Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches.
    Hirugen