2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1384):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-111179
    ML261
    		99.80%
    ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation.
    ML261
  • HY-13769A
    TPT-260 Dihydrochloride
    		≥98.0%
    TPT-260 Dihydrochloride (NSC55712) is a thiourea derivative.
    TPT-260 Dihydrochloride
  • HY-141490
    Beta-D-Glucopyranosyl nitromethane
    		99.94%
    Beta-D-Glucopyranosyl nitromethane, as a salt of a strongly basic anion exchanger in the OH cycle, is a glycosyl derivative of nitromethane.
    Beta-D-Glucopyranosyl nitromethane
  • HY-N6821
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid
    		99.58%
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid is a glucoside derivative of ascorbic acid, shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid.
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid
  • HY-B1442
    Acetylleucine
    		99.38%
    Acetylleucine (N-Acetyl-DL-leucine), orally active compound, can be used for the research of acute vestibular vertigo, cerebellar ataxia and nystagmus.
    Acetylleucine
  • HY-122273
    Pyrithiamine hydrobromide
    Pyrithiamine hydrobromide is a thiamine metabolic inhibitor that can act as a substrate for thiamine pyrophosphokinase. Pyrithiamine hydrobromide can be used in the research of nervous system diseases .
    Pyrithiamine hydrobromide
  • HY-P4486
    H-Pro-Gly-Pro-OH
    		98.47%
    H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia.
    H-Pro-Gly-Pro-OH
  • HY-158998
    ALKBH1-IN-2
    		99.16%
    ALKBH1-IN-2 (Compound 16) is a derivative of ALKBH1-IN-1 (HY-163385). ALKBH1-IN-2 is an ALKBH1 inhibitor. ALKBH1-IN-2 can modulate the 6mA levels.
    ALKBH1-IN-2
  • HY-B1785
    5-Sulfosalicylic acid
    5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell lines, with less toxicity. 5-Sulfosalicylic acid has antioxidant activities.
    5-Sulfosalicylic acid
  • HY-146748
    Sorbicillin
    		99.69%
    Sorbicillin, a sorbicillinoid analogue, acts as a potent anti-inflammation agent.
    Sorbicillin
  • HY-126247B
    (R)-BI-2852
    (R)-BI-2852 is the isomer of BI-2852 (HY-126247), and can be used as an experimental control. BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based agent design with nanomolar affinity. BI-2852 is mechanistically distinct from covalent KRASG12C inhibitor (binds to switch II pocket) and binds ten-fold more strongly to active KRASG12D versus KRASwt (740 nM vs 7.5 μM). BI-2852 blocks GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
    (R)-BI-2852
  • HY-131116
    Dihydrojasmonic acid
    		99.26%
    Dihydrojasmonic acid is a plant growth regulator.
    Dihydrojasmonic acid
  • HY-34611
    Boc-L-2,4-Diaminobutyric acid
    		≥98.0%
    Boc-L-2,4-Diaminobutyric acid is a derivative of L-2,4-Diaminobutyric acid (HY-101414)[1.
    Boc-L-2,4-Diaminobutyric acid
  • HY-B1044
    Idramantone
    		99.94%
    Idramantone (Kemantane), an Adamantane derivative, is an immunostimulant.
    Idramantone
  • HY-126126
    S-Adenosyl-DL-methionine
    		99.84%
    S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine.
    S-Adenosyl-DL-methionine
  • HY-122365
    Inositol nicotinate
    		98.05%
    Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters.
    Inositol nicotinate
  • HY-139167
    7-Hydroxywarfarin
    		99.39%
    7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity.
    7-Hydroxywarfarin
  • HY-139093A
    Paracetamol-cysteine TFA
    		≥99.0%
    Paracetamol-cysteine (TFA) is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005).
    Paracetamol-cysteine TFA
  • HY-N7138
    2-(Phosphonooxy)benzoic acid
    2-(Phosphonooxy)benzoic acid is a non-acetylated salicylic acid derivative which has the potential for inflammatory disease as well as in analgesic therapy.
    2-(Phosphonooxy)benzoic acid
  • HY-131501
    Menaquinone 9
    		≥98.0%
    Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase.
    Menaquinone 9