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  3. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118468
    Azothoate
    Azothoate is an active compound.
    Azothoate
  • HY-105368
    KF 22678
    KF 22678 is a thioester derivative of leinamycin. KF 22678 exhibits a broad antitumor spectrum against human carcinoma xenografts, including lung, colon, ovary, and prostate cancers. KF 22678 can be used for the study of cancer.
    KF 22678
  • HY-129290
    Flamprop-methyl
    Flamprop-methyl is an active compound.
    Flamprop-methyl
  • HY-49460
    WAY-639299
    98.0%
    WAY-639299 is an active molecule for research into amyloid diseases and synucleinopathies.
    WAY-639299
  • HY-N16498
    Kaempferol 3-rungioside
    Inhibitor
    Kaempferol 3-rungioside is a glycoside derivative of Kaempferol (HY-14590).
    Kaempferol 3-rungioside
  • HY-W674257
    WAY-658674
    98.0%
    WAY-658674 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-658674
  • HY-174240
    Anticancer agent 274
    Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma.
    Anticancer agent 274
  • HY-W750691
    Citranaxanthin
    Citranaxanthin is a carotenoid that can be isolated from Sea Hare Dolabella auriculari. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition.
    Citranaxanthin
  • HY-125338
    Psammaplysene B
    Psammaplysene B is an active compound.
    Psammaplysene B
  • HY-13976A
    PRL-8-53
    PRL-8-53 is a derivative of 2-PhenylethylaMine. PRL-8-53 is an orally active psychotropic agent.
    PRL-8-53
  • HY-W016509R
    epi-Inositol (Standard)
    epi-Inositol (Standard) is the analytical standard of epi-Inositol (HY-W016509). This product is intended for research and analytical applications. epi-Inositol, a inositol analog, is an antidepressant agent. epi-Inositol shows regulatory effects on expression of the most highly regulated gene in the inositol biosynthetic pathway. epi-Inositol shows antiepileptic effect.
    epi-Inositol (Standard)
  • HY-113613
    ETB067
    ETB067 is an active compound.
    ETB067
  • HY-N16419
    Haenamindole
    Haenamindole is an alkaloid. Haenamindole is promising for research of bacterial infection and cancers.
    Haenamindole
  • HY-131500
    SU-9055
    SU-9055 is an active compound.
    SU-9055
  • HY-47877
    WAY-300570
    98.0%
    N-(4-Chlorophenyl)-3-(4-oxo-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-3-yl)propanamide is an active molecule.
    WAY-300570
  • HY-125676
    Thermopterin
    Thermopterin is a derivative of the antimicrobial agent Pterin (HY-W037825) isolated from Methanoculleus thermophilus.
    Thermopterin
  • HY-133160
    Valproic acid hydroxamate
    Valproic acid hydroxamate (VPA-HA) has shown anticonvulsant activity in a mouse neural tube defect model, without any teratogenic effects.
    Valproic acid hydroxamate
  • HY-131390
    S-Ethylglutathione
    S-Ethylglutathione is a biochemical.
    S-Ethylglutathione
  • HY-115947
    Anticancer agent 33
    Anticancer agent 33 (compound 3), a Squamocin and Bullatacin derivative, is a potent anticancer agent. Anticancer agent 33 shows high potency to inhibit 4T1 breast cancer cell line (A549, HeLa, HepG2 and MCF-7 cells) growth with IC50s of 1.9-5.4 µM.
    Anticancer agent 33
  • HY-126071
    (-)-Mitorubrinic acid
    (-)-Mitorubrinic acid (Mitorubrinic acid) is a polyketide. (-)-Mitorubrinic acid is synthesis by two non-reducing polyketide synthase (PKS) genes (pks12 and pks11) in a sequential manner. (-)-Mitorubrinic is a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages.
    (-)-Mitorubrinic acid