2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-122036
    Flumedroxone acetate
    Flumedroxone acetate is an active compound.
    Flumedroxone acetate
  • HY-W674612
    WAY-297848
    		98.0%
    WAY-297848 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-297848
  • HY-120151
    3,5-Dinitro-p-toluic acid
    3,5-Dinitro-p-toluic acid is an active compound.
    3,5-Dinitro-p-toluic acid
  • HY-151342
    Ser@TPP@CUR
    Ser@TPP@CUR is a Curcumin (HY-N0005) derivative. Ser@TPP@CUR effectively ameliorates injured renal tubular epithelial cells and improves renal functions of acute kidney injury (AKI) mice. Ser@TPP@CUR can be used for the research of AKI .
    Ser@TPP@CUR
  • HY-129581
    Org 27759
    Org 27759 is an active compound.
    Org 27759
  • HY-177270
    CHNQD-01281
    CHNQD-01281, a derivative of Brefeldin A (HY-16592), is a EGFR modulator. CHNQD-01281 has strong antiproliferative activities against cancer cells (IC50: 0.079 and 0.081 μM for T24 and J82 cells, respectively). CHNQD-01281 regulates both EGFR/PI3K/AKT and EGFR/ERK pathways and mediates the chemotactic effect of chemokines on immune effector cells. CHNQD-01281 remarkably inhibits tumor growth in T24 xenograft mice model and prolongs the survival time in MB49 allogeneic mice model via inducing infiltration of cytotoxic T cells.
    CHNQD-01281
  • HY-W612557
    Edaravone dimer impurity
    Edaravone dimer impurity (Dimer 2) is a stable conjugated Edaravone (HY-B0099) dimer. Edaravone is a free radical scavenging agent for the study of acute ischemic stroke.
    Edaravone dimer impurity
  • HY-149683
    WAY-639228
    		≥98.0%
    WAY-639228-A is an active molecule.
    WAY-639228
  • HY-129953C
    5-trans Prostaglandin F2α tromethamine
    5-trans Prostaglandin F2α tromethamine is a derivative of 5-trans Prostaglandin F2α (HY-129953A). 5-trans Prostaglandin F2α is an endogenous metabolite present in blood that can be used for the research of myocardial infarction.
    5-trans Prostaglandin F2α tromethamine
  • HY-127036
    Tocamphyl
    Tocamphyl is an active compound.
    Tocamphyl
  • HY-124242
    (S)-α-Methylbenzyl ricinoleamide
    (S)-α-Methylbenzyl ricinoleamide (compound (R,S)-3d) is a fatty acid amide. (S)-α-Methylbenzyl ricinoleamide shows antiproliferative activity, inhibits the growth of human ovarian cancer cells NCI-ADR/RES and glioma cells U251 with GI50s of 1.9 μg/mL and 3.6 μg/mL, respectively.
    (S)-α-Methylbenzyl ricinoleamide
  • HY-129742
    JTT-010
    JTT-010 is an active compound.
    JTT-010
  • HY-115365
    (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol
    		≥98.0%
    (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol is a steroid-based allylic alcohol.
    (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol
  • HY-172664
    Trabectedin derivative 2
    Trabectedin derivative 2 is the derivative of Trabectedin. Trabectedin derivative 2 can be used for the research of cancer.
    Trabectedin derivative 2
  • HY-129726
    FR-900137
    FR-900137 is an active compound.
    FR-900137
  • HY-173533
    2-Chloro TNP-ITP tetrasodium
    2-Chloro TNP-ITP (2-Chloro TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706).
    2-Chloro TNP-ITP tetrasodium
  • HY-158806
    3,4-DHMA TFA
    3,4-DHMA (3,4-Dihydroxymethamphetamine) TFA is an active metabolite of 3,4-MDMA.
    3,4-DHMA TFA
  • HY-W338346
    Salicylate choline
    Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer.
    Salicylate choline
  • HY-133644
    Tribromoacetonitrile
    Tribromoacetonitrile is a nitrogen-containing disinfection byproduct.
    Tribromoacetonitrile
  • HY-164568
    7β,16α-Dihydroxybufalin
    7β,16α-Dihydroxybufalin is a dihydroxylated derivative of bufalin, which exhibits cytotoxicities against cancer cell lines.
    7β,16α-Dihydroxybufalin