2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1342):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0172AR
    Isoallolithocholic acid (Standard)
    Isoallolithocholic acid (Standard) is the analytical standard of Isoallolithocholic acid. This product is intended for research and analytical applications. Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation[1].
    Isoallolithocholic acid (Standard)
  • HY-49069
    Anti-osteoporosis agent-7
    		99.47%
    Anti-osteoporosis agent-7 (Compound 133) is a potential anti-osteoporosis agent showing high inhibition of osteoclast formation.
    Anti-osteoporosis agent-7
  • HY-164681
    Sunepitron
    Sunepitron is an active compound.
    Sunepitron
  • HY-113509A
    6-epi-Lipoxin A4
    6-epi-Lipoxin A4 is an active compound.
    6-epi-Lipoxin A4
  • HY-116148
    AHR-11797
    AHR-11797 is an active compound.
    AHR-11797
  • HY-122172
    GSK3-IN-6
    GSK3-IN-6 is an active compound.
    GSK3-IN-6
  • HY-116024
    Dimefuron
    Dimefuron is an active compound.
    Dimefuron
  • HY-159949
    YS10
    YS10 is a Tryptamine (HY-B2132) derivative. YS10 inhibits cell viability of SH-SY5Y cells with an IC50 of 0.44 nM.
    YS10
  • HY-173374
    DOTAGA-FAP-2286-ALB
    DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors.
    DOTAGA-FAP-2286-ALB
  • HY-P4079
    hCT(18-32)
    hCT(18-32) is a hCT (human calcitonin)-derived peptide.
    hCT(18-32)
  • HY-N6848
    Acetylseneciphylline N-oxide
    Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen is replaced by an acetyl group and the tertiary amino function is oxidised to the corresponding N-oxide.
    Acetylseneciphylline N-oxide
  • HY-114100
    Metesind
    Metesind is an active compound.
    Metesind
  • HY-131515R
    Tri-Salicylic acid (Standard)
    Tri-Salicylic acid (Standard) is the analytical standard of Tri-Salicylic acid. This product is intended for research and analytical applications. Tri-Salicylic acid is the compound with similar properties of salicylic acid. Tri-Salicylic acid has the potential for the research of inflammation, obesity and cardiovascular diseases (extracted from patent US20170368079A1, compound III).
    Tri-Salicylic acid (Standard)
  • HY-139388
    Para-fluoro methylaminorex
    Para-fluoro methylaminorex is a neuroactive compound.
    Para-fluoro methylaminorex
  • HY-120297
    S 9788
    S 9788 is a triazinoaminopiperidine derivative that acts as multidrug-resistance modulator.
    S 9788
  • HY-P4047
    Cyclo(RGDfK(Mal))
    Cyclo(RGDfK(Mal)) is a pentapeptide. Cyclo(RGDfK(Mal)) improves the attachment and infiltration of human pluripotent stem cells. Cyclo(RGDfK(Mal)) can be used for 3D stem cell culture and expansion.
    Cyclo(RGDfK(Mal))
  • HY-120759
    3-Hydroxy carvedilol
    3-Hydroxy carvedilol is an active compound.
    3-Hydroxy carvedilol
  • HY-123695
    5-HT4 antagonist 3
    5-HT4 antagonist 3 is an active compound.
    5-HT4 antagonist 3
  • HY-P4022
    Mca-Glu-Asp-Ala-Ser-Thr-Pro-Cys-OH
    Mca-Glu-Asp-Ala-Ser-Thr-Pro-Cys-OH is a L-Cysteine (HY-Y0337) derivative.
    Mca-Glu-Asp-Ala-Ser-Thr-Pro-Cys-OH
  • HY-169038
    11(Z),14(Z)-Eicosadienoic acid ethanolamide
    11(Z),14(Z)-Eicosadienoic acid ethanolamide (Compound 3) is an ethanolamide-conjugated form of 11(Z),14(Z)-Eicosadienoic acid (HY-149589). 11(Z),14(Z)-Eicosadienoic acid ethanolamide inhibits the inactivating transport of an endogenous cannabinoid substance with an IC50 value of 10.6 μM. 11(Z),14(Z)-Eicosadienoic acid ethanolamide can be used for research of neuropsychiatric conditions.
    11(Z),14(Z)-Eicosadienoic acid ethanolamide