2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W024067
    WAY-608119
    		99.31%
    WAY-608119 is an active molecule.
    WAY-608119
  • HY-170472
    Bpin-Bedaquiline
    Bpin-Bedaquiline (compound 2) is a boronic ester precursor of Bedaquiline (HY-14881). Bpin-Bedaquiline can react with H476Br to synthesize 76Br-Bedaquiline.
    Bpin-Bedaquiline
  • HY-B1556
    Benzyl salicylate
    		99.95%
    Benzyl salicylate (NSC 6647)?is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
    Benzyl salicylate
  • HY-I0180A
    Ticagrelor EP Impurity E hydrochloride
    		Control 99.96%
    Ticagrelor EP Impurity E hydrochloride is a conformationally restricted phenethylamine.
    Ticagrelor EP Impurity E hydrochloride
  • HY-114531
    Lomifylline
    		99.67%
    Lomifylline is a derivative of Xanthine (HY-W017389). Lomifylline can be used in research of sepsis and septic or endotoxic shock, when combined with an antibody to TNF or a TNF binding fragment.
    Lomifylline
  • HY-W024939
    2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene
    		98.69%
    2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene (2-Amino-3-o-chlorobenzoyl-5-ethylthiophenefandachem) is a benzophenone.
    2-Amino-3-(2-chlorobenzoyl)-5-ethylthiophene
  • HY-124479A
    γ-Lumicolchicine
    		99.70%
    γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569) that can be used as an experimental control for Colchicine action.
    γ-Lumicolchicine
  • HY-113490
    15-KETE
    		≥99.0%
    15-KETE (15-KETE) is produced by oxidation of the 15-hydroxyl of 15-HETE.
    15-KETE
  • HY-B0931
    Citiolone
    		99.44%
    Citiolone is a derivative of cysteine and has the potential for research in liver diseases.
    Citiolone
  • HY-125938
    Cycloartenyl ferulate
    		98.98%
    Cycloartenyl ferulate (Cycloartenol ferulate; Cycloartenol ferulic acid ester) is a derivative of γ-oryzanol (HY-B2194) with multiple biological activities including antioxidant, anti-inflammatory, and anti-tumor properties. Cycloartenyl ferulate selectively binds to IFNγR1 (binding affinity Kd = 0.5 μM) to activate the canonical JAK1/2-STAT1 signaling pathway. Cycloartenyl ferulate inhibits paraquat (PQ)-triggered apoptosis and ROS in HK2 cells. Cycloartenyl ferulate enhances the activation and cytolytic activity of natural killer (NK) cells by upregulating the expression of NK cell activation receptors (NKG2D, NKp30, NKp44) and the release of cytotoxic molecules and cytokine IFNγ. Cycloartenyl ferulate exerts anti-cancer effects in tumor mice models. Cycloartenyl ferulate can be used for the study of cancer and allergic inflammation intervention.
    Cycloartenyl ferulate
  • HY-105946A
    Hidrosmin (mixture)
    Hidrosmin (mixture) is a mixture of 3,5-di-O-(hydroxyethyl)diosmin and 3'-mono-O-(hydroxyethyl)diosmin.
    Hidrosmin (mixture)
  • HY-101595
    RPH-2823
    		≥99.0%
    RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance.
    RPH-2823
  • HY-W026842
    2-Benzoylbenzoic acid
    		99.81%
    2-Benzoylbenzoic acid is a Benzophenone (HY-Y0546) analog. 2-Benzoylbenzoic acid is non-phototoxic due to the alteration of the functional groups. 2-Benzoylbenzoic acid can be used to study the mechanism of phototoxicit.
    2-Benzoylbenzoic acid
  • HY-34781
    4'-Trifluoromethyl-2-biphenyl carboxylic acid
    		99.91%
    4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent.
    4'-Trifluoromethyl-2-biphenyl carboxylic acid
  • HY-W004286
    Methyl laurate
    		99.90%
    Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid.
    Methyl laurate
  • HY-145554
    Bafrekalant
    		99.67%
    Bafrekalant is a diazabicyclic substituted imidazo[l,2-a]pyrimidine-derivative. Bafrekalant has the potential for the research of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring (extracted from patent WO2018228907A1).
    Bafrekalant
  • HY-B1714
    NSC 601980 analog
    		98.0%
    NSC 601980 analog is an analogue of NSC601980. In yeast screening experiments, NSC 601980 exhibited antitumor activity, effectively inhibiting cell proliferation in both COLO 205 and HT29 cell lines, with Log GI 50 values of -6.6 and -6.9, respectively.
    NSC 601980 analog
  • HY-76665
    Anticancer agent 209
    		≥99.0%
    Anticancer agent 209 (compound 1) is an anticancer agent. Anticancer agent 209 exhibits cytotoxic activity against colon cancer in vitro.
    Anticancer agent 209
  • HY-101556
    Namirotene
    		99.33%
    Namirotene (CBS-211A) is a retinoic acid analog, which is utilized in topical eye administration. Namirotene enhances 1α,25-dihydroxyvitamin D3-induced cytotoxicity in cell U937 and induces the differentation in U937.
    Namirotene
  • HY-123358
    AR-H049020XX
    AR-H049020XX is an active compound.
    AR-H049020XX