2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. ClpP
  5. ClpP Modulator

ClpP Modulator

ClpP Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-175597
    ClpP modulator-1
    		Modulator
    ClpP modulator-1 (Compound BC8a), a peptidomimetic, is an allosteric ClpP modulator. ClpP modulator-1 is a ClpP activator at low concentration with EC50s of 0.35 and 0.58  μM for for Neisseria meningitides ClpP (NmClpP) and Escherichia coli ClpP (EcClpP), resepectively. ClpP modulator-1 also inhibits peptidase activity at high concentration by competitively inhibiting substrate protein (LY-AMC) binding to ClpP C sites. ClpP modulator-1 has antibacterial activity. ClpP modulator-1 can be used for bacterial infections research.