2. Signaling Pathways
  3. Immunology/Inflammation
  4. CD47
  5. CD47 Activator

CD47 Activator

CD47 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-P11205
    Cys-PKHB1
    		Activator
    Cys-PKHB1 (Cys-txCD47) is a peptide conjugated to PKHB1, a CD47 agonist peptide and a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. PKHB1 induces immune system activation in breast cancer cells through immunogenic cell death.