2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

Related Products

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-A0276A
    Gentamicin
    Gentamicin, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC50 of 0.57 mM.
    Gentamicin
  • HY-B0132
    Norfloxacin
    		98.31%
    Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
    Norfloxacin
  • HY-A0086
    Netilmicin sulfate
    		≥98.0%
    Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL.
    Netilmicin sulfate
  • HY-B0435
    Roxithromycin
    		99.86%
    Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects.
    Roxithromycin
  • HY-W750960
    Biotinylated isoxazole
    		99.41%
    Biotinylated isoxazole is a biotinylated derivative of Isoxazole (HY-W010649). Biotinylated isoxazole is capable of triggering the formation of aggregates related to RNA granules.
    Biotinylated isoxazole
  • HY-14989
    SQ109
    		98.24%
    SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent.
    SQ109
  • HY-17574
    Thio-TEPA
    		99.49%
    Thio-TEPA is a DNA alkylating agent, with antitumor activity.
    Thio-TEPA
  • HY-B0509
    Amikacin hydrate
    		99.93%
    Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria.
    Amikacin hydrate
  • HY-A0090
    Nitrofurantoin
    		99.71%
    Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
    Nitrofurantoin
  • HY-14865C
    Omadacycline hydrochloride
    		99.47%
    Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections.
    Omadacycline hydrochloride
  • HY-B0356B
    Ciprofloxacin hydrochloride monohydrate
    		99.88%
    Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin hydrochloride monohydrate
  • HY-14737
    Ceftaroline fosamil
    		99.81%
    Ceftaroline fosamil (TAK-599), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil can be used for the research of MRSA infection.
    Ceftaroline fosamil
  • HY-N6727
    Gliotoxin
    		99.51%
    Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of macrophages and the immune functions of other immune cells . Gliotoxin inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis. Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus internalization into lung epithelial cells. Gliotoxin is a potent NOTCH2 transactivation inhibitor, can effectively induce apoptosis of chronic lymphocytic leukemia (CLL) cells.
    Gliotoxin
  • HY-B1327
    Chlortetracycline hydrochloride
    Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline hydrochloride
  • HY-19892A
    Brilacidin tetrahydrochloride
    		99.10%
    Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin tetrahydrochloride is a defensin mimetic antibiotic compound.
    Brilacidin tetrahydrochloride
  • HY-B0210A
    Cefoperazone sodium salt
    		99.72%
    Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.
    Cefoperazone sodium salt
  • HY-B0479
    Thiamphenicol
    		99.63%
    Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria).
    Thiamphenicol
  • HY-15527
    Emapunil
    		Inhibitor 99.94%
    Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models.
    Emapunil
  • HY-106101
    Echinomycin
    		98.57%
    Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM.
    Echinomycin
  • HY-B1150
    Clofoctol
    		99.93%
    Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency.
    Clofoctol
Antibiotic Isoform Comparison

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