Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1619):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W142047

Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline
Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline is a proline derivative.

HY-P2401

Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH
Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

HY-151637

Fmoc-N-propargyl-MPBA
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures. Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P4716

Boc-D-Trp(For)-OH
Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory.

HY-W710387

Ethyl Lauroyl Arginate Hydrochloride-d₂₃
Ethyl Lauroyl Arginate Hydrochloride-d₂3 is the deuterium labeled Ethyl Lauroyl Arginate Hydrochloride (HY-W099595). Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative.

HY-W769169

N-Isobutyrylglycine-¹³C₂,¹⁵N
N-Isobutyrylglycine-¹³C₂,¹⁵N is the ¹³C- and ¹⁵N-labeled N-Isobutyrylglycine (HY-W141928). N-Isobutyrylglycine is a Glycine (HY-Y0966) derivative.

HY-W019263

2-Amino-4,4,4-trifluorobutyric acid
2-Amino-4,4,4-trifluorobutyric acid is an alanine derivative.

HY-114729

Leucylproline
Leucylproline, a dipeptide, plays important roles in the medium-dependent regulation of proteinase activity.

HY-W142126

N-Carbobenzoxy-DL-norvaline
N-Carbobenzoxy-DL-norvaline is a valine derivative.

HY-W011444

Z-D-Ser(TBu)-OH
Z-D-Ser(TBu)-OH is a serine derivative.

HY-W014238

S-tert-Butyl-L-cysteine hydrochloride		98.0%
S-tert-Butyl-L-cysteine hydrochloride is a cysteine derivative.

HY-W141990

L-Allysine ethylene acetal
L-Allysine ethylene acetal is a lysine derivative.

HY-W013810

(tert-Butoxycarbonyl)-L-arginine hydrochloride
(tert-Butoxycarbonyl)-L-arginine hydrochloride is an arginine derivative.

HY-W040441

(S)-Methyl 2-amino-3-(3-hydroxyphenyl)propanoate hydrochloride		99.82%
(S)-Methyl 2-amino-3-(3-hydroxyphenyl)propanoate hydrochloride is a phenylalanine derivative.

HY-131112

N-Pivaloyl-L-tyrosine
N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.

HY-P4603

H-Asp-Ala-OH
H-Asp-Ala-OH is adipeptide.

HY-W012003

(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid
(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid is a Glycine (HY-Y0966) derivative.

HY-W011004

(S)-4-Amino-5-(((S)-1-(((S)-1-carboxy-2-phenylethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid
(S)-4-Amino-5-(((S)-1-(((S)-1-carboxy-2-phenylethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid is a phenylalanine derivative.

HY-W011892

Z-D-Thr-OH
Z-D-Thr-OH is a threonine derivative.

HY-W008140

N-Methylleucine
N-Methylleucine is a leucine derivative.

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