2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. ADAMTS
  5. ADAMTS Antagonist

ADAMTS Antagonist

ADAMTS Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-162284
    BAY-9835
    		Antagonist 99.46%
    BAY-9835, a chemical probe, is an orally active ADAMTS7 and ADAMTS12 antagonist with IC50s of 6 nM and 30 nM, respectively. BAY-9835 exhibits inhibitory potencies vs mouse (mIC50 = 8 nM) and rat (rIC50 = 27 nM) ADAMTS7 enzymes. BAY-9835 is very selective against a range of off-targets and metalloproteases. BAY-9835 can be used for the study of atherogenesis.