2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-154978
    Cisplatin-resistant cells-IN-1
    Cisplatin-resistant cells-IN-1 (Compound 8) has high cytotoxicity against Cisplatin (HY-17394)-resistant cells. Cisplatin-resistant cells-IN-1 reduces the metabolic activity effectively in the low nanomolar range (IC50: 0.14–1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells).
    Cisplatin-resistant cells-IN-1
  • HY-161042
    Neuroprotective agent 2
    Neuroprotective agent 2 (Compd 28) is a potent neuroprotective agent which has a protective effect in both salsolinol and glutamate-induced neurodegeneration models. Neuroprotective agent 2 reduces oxidative stress and caspase-3/7 activity in the glutamate model.
    Neuroprotective agent 2
  • HY-P990902A
    Atigotatug (FUT8-KO)
    Atigotatug (FUT8-KO) is an anti-fuc-GM1 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out, and fucose deficiency enhances the ADCC effect of the antibody. Atigotatug (HY-P990902) is a Fucosyl ganglioside GM1 (fuc-GM1)-targeting IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as small cell lung cancer.
    Atigotatug (FUT8-KO)
  • HY-149327
    Anticancer agent 131
    HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT116 cells with an IC50 of 5.59 μM.
    Anticancer agent 131
  • HY-139723
    Antidepressant agent 2
    		Inhibitor
    Antidepressant agent 2 exerts pronounced antidepressant activity (MED 0.1 mg/kg).
    Antidepressant agent 2
  • HY-158195
    DPP23
    		99.55%
    DPP23 exerts antitumor activity through ROS-mediated apoptosis in cancer cells, but does not play a role in healthy cells. DPP23 can up-regulate the expression of ATF4.
    DPP23
  • HY-P10931A
    RAD21 (356–395) TFA
    RAD21 (356–395) TFA is a peptide encompassing amino acids 356 to 395 of the RAD21 protein, which can be used to study the interaction mechanism between STAG1 and RAD21. The equilibrium dissociation constant (KD) value for the interaction between RAD21 (356–395) TFA and STAG1 is 127 nM.
    RAD21 (356–395) TFA
  • HY-106486A
    Butoprozine hydrochloride
    Butoprozine hydrochloride functions as a cardiac depressant agent.
    Butoprozine hydrochloride
  • HY-168068
    Res-Glu3
    Res-Glu3 is the derivative of Resveratrol (HY-16561). Res-Glu3 mitigates the ROS accumulation, and exhibits neuroprotective efficacy against H2O2-caused cellular damage in PC12. Res-Glu3 exhibits antioxidant activity in rats ischemia reperfusion models.
    Res-Glu3
  • HY-121595
    5,5-Diphenylbarbituric acid
    5,5-Diphenylbarbituric acid is an organic compound belonging to the derivatives of barbituric acid. 5,5-Diphenylbarbituric acid can be used for seizure study.
    5,5-Diphenylbarbituric acid
  • HY-163009
    Dicamba-butyric acid
    Dicamba-butyric acid is an immunizing and heterologous hapten.
    Dicamba-butyric acid
  • HY-116131
    DAC-2-25
    DAC-2-25 is a molecule that causes a homeotic transformation of body column into tentacle zone.
    DAC-2-25
  • HY-W013576
    Methyl 2-Octynoate
    		99.78%
    Methyl 2-Octynoate is a hapten.
    Methyl 2-Octynoate
  • HY-149216
    Anticancer agent 103
    Anticancer agent 103 (Compound 2k) is a potent anticancer agent.
    Anticancer agent 103
  • HY-P11009
    SA-21
    SA-21 is a 21-amino acid polymer peptide (Ac-RLIEDICLPRWGCLWEDD-NH2) that binds to ligands of urokinase-type plasminogen activator, Fab antibody fragments, and small proteins. SA-21 can be used to purify albumin (Ki=1.9 μM).
    SA-21
  • HY-W176012
    Glycolate oxidase-IN-1
    Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1).
    Glycolate oxidase-IN-1
  • HY-103641AR
    (2S)-Octyl-α-hydroxyglutarate (Standard)
    CVT-2738 (Standard) is the analytical standard of CVT-2738. This product is intended for research and analytical applications. CVT-2738 is a Ranolazine (HY-B0280) Metabolite, and shows anti-myocardial ischemia activities.
    (2S)-Octyl-α-hydroxyglutarate (Standard)
  • HY-P991691
    Inclocibart
    Inclocibart is a humanized IgG4 lambda1 antibody targeting SERPINF2. The corresponding isotype control is Human IgG4 lambda1, Isotype Control (HY-P99987).
    Inclocibart
  • HY-106424
    Soretolide
    Soretolide is an antiepileptic agent. Soretolide is effective in maximal electroshock-induced seizure (MES) test in rodents. Soretolide inhibits metabolism of Phenytoin (HY-B0448). Soretolide exhibits a good pharmacokinetic character in rats model.
    Soretolide
  • HY-W550494
    1-(Pyridin-4-yl)heptan-1-one
    1-(Pyridin-4-yl)heptan-1-one (Compound R=n-C₆H₁₃) is an anticonvulsant agent. 1-(Pyridin-4-yl)heptan-1-one can protect mice from electroshock-induced convulsions. 1-(Pyridin-4-yl)heptan-1-one is promising for research of convulsion-related diseases such as epilepsy.
    1-(Pyridin-4-yl)heptan-1-one
Cat. No. Product Name / Synonyms Application Reactivity