2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N4148
    Purpureaside C
    		99.40%
    Purpureaside C is a phenolic glycoside and has significant proinflammatory action.
    Purpureaside C
  • HY-W009371C
    D-Ribose 5-phosphate disodium dihydrate
    		99.00%
    D-Ribose 5-phosphate disodium dihydrate is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids.
    D-Ribose 5-phosphate disodium dihydrate
  • HY-W017462S
    Creatine-d5 monohydrate
    		99.93%
    Creatine-d5 (monohydrate) is the deuterium labeled Creatine monohydrate. Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
    Creatine-d<sub>5</sub> monohydrate
  • HY-N0073
    Sarsasapogenin
    		99.91%
    Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.
    Sarsasapogenin
  • HY-113150
    Hexanoylglycine
    		99.67%
    Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy.
    Hexanoylglycine
  • HY-131368
    α,α-Trehalose 6-phosphate potassium
    		99.00%
    α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP).
    α,α-Trehalose 6-phosphate potassium
  • HY-B1960
    Canthaxanthin
    		≥99.0%
    Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.
    Canthaxanthin
  • HY-116084S
    Trimethylamine N-oxide-d9
    		99.76%
    Trimethylamine N-oxide-d9 is the deuterium labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
    Trimethylamine N-oxide-d<sub>9</sub>
  • HY-B1204S
    Histamine-α,α,β,β-d4 dihydrochloride
    		98.0%
    Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
    Histamine-α,α,β,β-d<sub>4</sub> dihydrochloride
  • HY-113511
    Glycogen, Mussel
    		99.3%
    Glycogen, Mussel is a glycolytic intermediates and high-energy phosphates that can serve as a form of energy storage in humans, animals, fungi, and bacteria.
    Glycogen, Mussel
  • HY-P2997
    γ-glutamyltransferase, Porcine kidney
    γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research.
    γ-glutamyltransferase, Porcine kidney
  • HY-W010040
    4-​Hydroxyphenylpyruvic acid
    		98.63%
    4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase. 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria.
    4-​Hydroxyphenylpyruvic acid
  • HY-W012926
    Dihydrouracil
    		99.94%
    Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient.
    Dihydrouracil
  • HY-N7389A
    GDP-D-mannose disodium
    		99.92%
    GDP-D-mannose disodium contains GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).
    GDP-D-mannose disodium
  • HY-101952R
    Prostaglandin E2 (Standard)
    Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2 (Standard)
  • HY-N7404
    Nε,Nε,Nε-Trimethyllysine chloride
    		99.14%
    Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA).
    Nε,Nε,Nε-Trimethyllysine chloride
  • HY-104026S
    L-Kynurenine-d4
    		99.59%
    L-Kynurenine-d4 is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].
    L-Kynurenine-d<sub>4</sub>
  • HY-NP155
    Histone (calf thymus)
    Histone (calf thymus) is a histone found in the deoxyribonucleoprotein of calf thymus and can be obtained by acid extraction technique.
    Histone (calf thymus)
  • HY-W007566
    5-Methoxyindole-3-acetic acid
    		99.60%
    5-Methoxyindole-3-acetic acid is a metabolite of Melatonin (HY-B0075). 5-Methoxyindole-3-acetic acid significantly prolongs the estrous cycle, increases uterine weight, and induces ovarian follicular cysts in female rats, while also regulating the levels of related hormones.
    5-Methoxyindole-3-acetic acid
  • HY-W008091
    5-Methylcytosine
    		99.94%
    5-Methylcytosine is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma.
    5-Methylcytosine
Cat. No. Product Name / Synonyms Application Reactivity