2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N2026
    Propylparaben
    		99.76%
    Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats.
    Propylparaben
  • HY-B1271
    Sulfinpyrazone
    		98.08%
    Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects.
    Sulfinpyrazone
  • HY-113200A
    N1-Acetylspermine trihydrochloride
    		99.90%
    N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia.
    N1-Acetylspermine trihydrochloride
  • HY-100551
    meso-Erythritol
    		99.73%
    meso-Erythritol is a sugar alcohol that found in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and can be used as low-calorie sweetener food additives.
    meso-Erythritol
  • HY-101952S
    Prostaglandin E2-d4
    		99.90%
    Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2-d<sub>4</sub>
  • HY-B1391
    D-Panthenol
    		99.98%
    D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.
    D-Panthenol
  • HY-101410S
    SDMA-d6
    		98.07%
    SDMA-d6 is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity.
    SDMA-d<sub>6</sub>
  • HY-W011552
    2'-O-Methyladenosine
    		99.76%
    2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine
  • HY-W013715A
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM)
    		98.06%
    Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA.
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM)
  • HY-A0181A
    Adenosine 5'-monophosphate monohydrate
    		99.81%
    Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2.
    Adenosine 5'-monophosphate monohydrate
  • HY-P2979
    Invertase, baker's yeast (S. cerevisiae)
    Invertase, baker's yeast (S. cerevisiae) is a major enzyme present in plants and microorganisms, is often used in biochemical studies. Invertase catalyzes the hydrolysis of the disaccharide sucrose into glucose and fructose.
    Invertase, baker's yeast (S. cerevisiae)
  • HY-128851B
    Coenzyme A sodium
    		99.46%
    Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids.
    Coenzyme A sodium
  • HY-W008646
    7,8-Dihydro-L-biopterin
    		99.79%
    7,8-Dihydro-L-biopterin is an oxidation product of tetrahydrobiopterin.
    7,8-Dihydro-L-biopterin
  • HY-66005S
    Acetaminophen-d4
    		99.60%
    Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d<sub>4</sub>
  • HY-W018772
    D-Ribose(mixture of isomers)
    		≥98.0%
    D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner.
    D-Ribose(mixture of isomers)
  • HY-W020014
    Pyruvic aldehyde (40% in water)
    Pyruvic aldehyde (40% in water) is often used as a reagent in organic synthesis, as a flavoring agent, and in tanning.
    Pyruvic aldehyde (40% in water)
  • HY-113166
    Dodecanoylcarnitine
    		99.75%
    Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma.
    Dodecanoylcarnitine
  • HY-W005255
    3-(3-Hydroxyphenyl)propionic acid
    		99.89%
    3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases.
    3-(3-Hydroxyphenyl)propionic acid
  • HY-P0240
    Tuftsin
    		99.65%
    Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.
    Tuftsin
  • HY-W002292
    L-Homoserine
    		99.88%
    L-Homoserine is a nonessential chiral amino acid and the precursor of L-Threonine (HY-N0658) and L-Methionine (HY-N0326). L-Homoserine wide applications in the fields of pharmaceutical, agricultural, cosmetic and fragrance industries.
    L-Homoserine
Cat. No. Product Name / Synonyms Application Reactivity