2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1271
    Sulfinpyrazone
    		98.08%
    Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects.
    Sulfinpyrazone
  • HY-W010388S1
    Creatine-d3
    		98.95%
    Creatine-d3 is the deuterium labeled Creatine (HY-W010388). Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
    Creatine-d<sub>3</sub>
  • HY-N7148
    γ-Tocopherol
    		99.63%
    γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity.
    γ-Tocopherol
  • HY-128851B
    Coenzyme A sodium
    		99.46%
    Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids.
    Coenzyme A sodium
  • HY-W015967
    Glycolic acid
    Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
    Glycolic acid
  • HY-128738
    Thymidine-5'-monophosphate (disodium) salt
    		99.79%
    Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
    Thymidine-5'-monophosphate (disodium) salt
  • HY-B1189
    Meglutol
    		≥98.0%
    Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases.
    Meglutol
  • HY-113432
    Nudifloramide
    		99.94%
    Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro.
    Nudifloramide
  • HY-113166
    Dodecanoylcarnitine
    		99.75%
    Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma.
    Dodecanoylcarnitine
  • HY-128748
    DL-Glyceraldehyde
    DL-Glyceraldehyde is a bioactive substance involved in cellular energy metabolism and a key intermediate in sugar metabolism pathways (such as glycolysis and gluconeogenesis). During glycolysis, DL-Glyceraldehyde is converted by enzymes into other metabolites to provide energy for cells; during gluconeogenesis, DL-Glyceraldehyde participates in the synthesis of glucose as a precursor. In the field of medical research, DL-Glyceraldehyde can be used to study diseases related to sugar metabolism, such as diabetes, tumors, etc[1][2].
    DL-Glyceraldehyde
  • HY-N0148A
    Rutin hydrate
    		98.99%
    Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress.
    Rutin hydrate
  • HY-P0240
    Tuftsin
    		99.65%
    Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.
    Tuftsin
  • HY-143712
    Allolithocholic acid
    		99.69%
    Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver.
    Allolithocholic acid
  • HY-I0352
    Epiandrosterone
    		99.96%
    Epiandrosterone is a steroid hormone. Epiandrosterone activates BKCa. Epiandrosterone inhibits glucose transport and insulin release. Epiandrosterone has weak androgenic activity.
    Epiandrosterone
  • HY-101410S
    SDMA-d6
    		98.07%
    SDMA-d6 is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity.
    SDMA-d<sub>6</sub>
  • HY-N0390S
    L-Glutamine-15N
    		99.6%
    L-Glutamine-15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-<sup>15</sup>N
  • HY-Y0252S
    L-Proline-13C5
    		99.00%
    L-Proline-13C5 is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
    L-Proline-<sup>13</sup>C<sub>5</sub>
  • HY-W010040
    4-​Hydroxyphenylpyruvic acid
    		98.63%
    4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase. 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria.
    4-​Hydroxyphenylpyruvic acid
  • HY-104026S
    L-Kynurenine-d4
    		99.59%
    L-Kynurenine-d4 is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].
    L-Kynurenine-d<sub>4</sub>
  • HY-B2162A
    Chondroitin sulfate sodium (from shark cartilage)
    		99.52%
    Chondroitin sulfate sodium (from shark cartilage), one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs.
    Chondroitin sulfate sodium (from shark cartilage)
Cat. No. Product Name / Synonyms Application Reactivity