2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. MMP
  5. MMP-9 Isoform
  6. MMP-9 Activator

MMP-9 Activator

MMP-9 Activators (3):

Cat. No. Product Name Effect Purity
  • HY-178477
    LIFR/GPBAR1 modulator 1
    		Activator
    LIFR/GPBAR1 modulator 1 is an orally active, potent GPBAR1 agonist (EC50 = 0.2 μM) and LIFR inhibitor (IC50 = 7.9 μM). LIFR/GPBAR1 modulator 1 upregulates leukaemia inhibitory factor (LIF)-mediated mRNA expression of LIFR and GPBAR1 and significantly reduces the expression of pro-fibrosis markers (COL1A1, ASMA, and TGFβ), and reduces TIMP1 expression and increases MMP9 expression. LIFR/GPBAR1 modulator 1 can be used for the study of human fibrotic disorders.
  • HY-N0785
    Ginkgolide C
    		Activator 99.67%
    Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.
  • HY-P3513
    β-Neo-Endorphin
    		Activator 99.32%
    β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9.