2. Signaling Pathways
  3. Autophagy
  4. LRRK2
  5. LRRK2 Degrader

LRRK2 Degrader

LRRK2 Degraders (3):

Cat. No. Product Name Effect Purity
  • HY-178796
    PROTAC LRRK2 Degrader-4
    		Degrader
    PROTAC LRRK2 Degrader-4 is a PROTAC LRRK2 degrader with a DC50 of 0.79 nM. PROTAC LRRK2 Degrader-4 can be used for research in Parkinson’s disease and inflammation. (Pink: LRRK2 ligand: LRRK2-IN-19 (HY-177016); Black: Linker (HY-178831); Blue: E3 ligand (HY-179222); E3+Linker (HY-178832).
  • HY-163064
    CC-3240
    		Degrader 98.23%
    CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with the IC50 of 9 nM.
  • HY-178797
    PROTAC LRRK2 Degrader-3
    		Degrader
    PROTAC LRRK2 Degrader-3 is a PROTAC LRRK2 degrader with a DC50 of 0.17 nM. PROTAC LRRK2 Degrader-3 can be used for research in Parkinson’s disease and inflammation. (Pink: LRRK2 ligand: LRRK2-IN-19 (HY-177016); Black: Linker (HY-178830); Blue: E3 ligand (HY-163927); E3+Linker (HY-178828)).