2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. Integrin Ligand

Integrin Ligand

Integrin Isoform Comparison

Integrin Ligands (8):

Cat. No. Product Name Effect Purity
  • HY-P990764
    Sigvotatug
    		Ligand 99.67%
    Sigvotatug is an anti-ITGB6 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-P5098
    E(c(RGDfK))2
    		Ligand 99.42%
    E(c(RGDfK)) is an αvβ3 integrin-specific binding moiety with tumor targeting properties. Increased uptake of E(c(RGDfK)) in human ovarian cancer OVCAR-3 xenograft tumors may be useful in cancer research.
  • HY-P990764B
    Sigvotatug (Biotinylated)
    		Ligand ≥99.0%
    Sigvotatug (Biotinylated) is a biotinylated derivative of Sigvotatug (HY-P990764). Sigvotatug (Biotinylated) is a humanized IgG1 κ monoclonal antibody inhibitor against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-176300
    RGD-DA6
    		Ligand
    RGD-DA6 is an αvβ3-targeted ligand. RGD-DA6 consists of RGDfK (an integrin αvβ3-targeted RGD peptide), DOTADG, d-Glu, Lys, AMBA, and IPBA. RGD-DA6 can be radiolabeled as an αvβ3-targeted radioligand and used for high-contrast tumor imaging and enhanced anticancer efficacy.
  • HY-P3530
    G-{d-Arg}-GDSP
    		Ligand
    G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption.
  • HY-P1897
    Fibronectin Active Fragment Control
    		Ligand
    Fibronectin Active Fragment Control is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins.
  • HY-P11339
    c-RGD-SH
    		Ligand
    c-RGD-SH is an Integrin αvβ3 ligand. c-RGD-SH conjugated with core-crosslinked polymeric micelles (CCPM) can be used for synthesis a dual modality nanoparticle probe, and this probe labeled with both Cy7 and 111In can be used for SPECT and NIRF imaging of tumor.
  • HY-P11328
    GFOGER peptide
    		Ligand
    GFOGER peptide is a α2β1, α1β1 and α11β1 integrin ligand peptide. GFOGER peptide can be recognized via directly interactions of integrins with its Glu and Arg residues, particularly binding to Glu through the metal ion-dependent adhesion site (MIDAS).