IRAK Inhibitors

IRAK1

IRAK4

IRAK Degraders, Inhibitors & Modulators

Product Name	IRAK1	IRAK4	Purity
Zimlovisertib		IRAK4, IC₅₀: .2 nM	99.94%
KT-474		IRAK4	99.77%
Ginsenoside Rb1	IRAK-1		99.75%
AS2444697		IRAK4, IC₅₀: 21 nM	99.54%
Emavusertib		IRAK4, IC₅₀: 57 nM	99.97%
Lomonitinib		IRAK4
JH-X-119-01	IRAK-1, IC₅₀: 9 nM		99.03%
Zabedosertib		IRAK4, IC₅₀: 3.55 nM	98.14%
HS-276	IRAK1, IC₅₀: 264 nM	IRAK4, IC₅₀: 2500 nM	98.93%
JNJ-1013	IRAK1, IC₅₀: 72 nM	IRAK4, IC₅₀: 443 nM	99.80%
AZ1495	IRAK1, IC₅₀: 23 nM	IRAK4, IC₅₀: 5 nM	98.07%
KME-2780	IRAK1, IC₅₀: 19 nM	IRAK4, IC₅₀: 0.5 nM	98.94%
JH-X-119-01 hydrochloride	IRAK1		99.14%
IRAK4-IN-4		IRAK4, IC₅₀: 2.8 nM	99.55%
PROTAC IRAK4 degrader-1		IRAK4	99.77%
KTX-951		IRAK4, Kd: 3.5 nM IRAK4, DC₅₀: 18 nM	98.03%
Trimebutine maleate	IRAK-1		99.91%
HS-243	IRAK-1, IC₅₀: 24 nM	IRAK4, IC₅₀: 20 nM	99.95%
Trimebutine	IRAK-1		99.42%
IRAK4-IN-7		IRAK4	99.36%
PROTAC IRAK4 degrader-3		IRAK4
Larotinib mesylate hydrate	IRAK-1, IC₅₀: 167 nM		98.66%
PF-06426779		IRAK4, IC₅₀: 0.3 nM	99.89%
Larotinib	IRAK1, IC₅₀: 167 nM		99.50%
IRAK4-IN-20		IRAK4, IC₅₀: 3.55 nM
IRAK-4 protein kinase inhibitor 2		IRAK4, IC₅₀: 4 μM	98.01%
IRAK1/4/pan-FLT3 Kinase-IN-1	IRAK-1, IC₅₀: 5 nM	IRAK4, IC₅₀: 0.6 nM	98.66%
GLPG2534	IRAK1, IC₅₀: 179 nM	hIRAK4, IC₅₀: 6.4 nM mIRAK4, IC₅₀: 3.5 nM	98.73%
IRAK4-IN-14		IRAK4, IC₅₀: 0.003 μM	99.01%
IRAK inhibitor 4 (trans)		IRAK4	99.02%
HS271		IRAK4, IC₅₀: 7.2 μM	99.92%
IRAK inhibitor 4		IRAK4	99.77%
Ginsenoside Rb1 (Standard)	IRAK-1
Emavusertib hydrochloride		IRAK4, IC₅₀: 57 nM
IRAK4-IN-8		IRAK4
IRAK4-IN-18		IRAK4, IC₅₀: 15 nM
PROTAC IRAK4 degrader-5		IRAK4
IRAK4-IN-16		IRAK4, IC₅₀: 2.5 ± 0.8 nM
PROTAC IRAK4 ligand-4		IRAK4
IRAK4-IN-9		IRAK4, IC₅₀: 1.5 nM
IRAK4-IN-10		IRAK4, IC₅₀: 1.5 nM
IRAK4-IN-13		IRAK4, IC₅₀: 0.6 nM
PROTAC IRAK4 degrader-13		IRAK4
IRAK4-IN-31		IRAK4
IRAK4 modulator-1		IRAK4, IC₅₀: 4.647 μM (^[1])
DW18134		IRAK4, IC₅₀: 11.2 nM
PROTAC IRAK4 degrader-2		IRAK4
KTX-612		IRAK4, DC₅₀: 7 nM
AF-45	IRAK1, IC₅₀: 1765 nM	IRAK4, IC₅₀: 128 nM
BIO-8169		IRAK4, IC₅₀: 0.23 nM
PROTAC IRAK4 degrader-4		IRAK4
BIO-7488		hIRAK4, IC₅₀: 0.6 nM	99.44%
KTX-497		IRAK4, DC₅₀: 3 nM
KTX-955		IRAK4, IC₅₀: 5 nM
IRAK4-IN-15		IRAK4, IC₅₀: 0.002 μM
IRAK4-IN-12		IRAK4, IC₅₀: 0.015 μM
IRAK4-IN-30		IRAK4, IC₅₀: 0.6 nM
IRAK4-IN-17		IRAK4, IC₅₀: 1.3 nM
PROTAC IRAK4 degrader-6		IRAK4
APH02174		IRAK4, DC₅₀: 4.01 nM
IRAK4-IN-11		IRAK4, IC₅₀: .008 μM
IRAK4-IN-19		IRAK4, IC₅₀: 4.3 nM
HG-12-6		IRAK4, IC₅₀: 165 nM (Unphosphorylated inactive IRAK4 ) IRAK4, IC₅₀: 2876 nM (Phosphorylated active IRAK4 )
GNE-2256		IRAK4, Ki: 1.4 nM
IRAK4-IN-24		IRAK4
IRAK4-IN-27		IRAK4, IC₅₀: 8.7 nM
Trimebutine-d₃ hydrochloride	IRAK-1
Trimebutine-d₅ fumarate	IRAK-1
Trimebutine maleate (Standard)	IRAK-1
Trimebutine (Standard)	IRAK-1
IRAK4-IN-32		IRAK4

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