2. Signaling Pathways
  3. Immunology/Inflammation
  4. COX
  5. COX Isoform

COX

 

COX Related Products (629):

Cat. No. Product Name Effect Purity
  • HY-101481R
    Flurbiprofen axetil (Standard)
    		Inhibitor
    Flurbiprofen axetil (Standard) is the analytical standard of Flurbiprofen axetil. This product is intended for research and analytical applications. Flurbiprofen axetil is a non-selective cyclooxygenase (COX) inhibitor. Flurbiprofen axetil has anti-inflammatory effect.
  • HY-B0559R
    Nabumetone (Standard)
    		Inhibitor
    Nabumetone (Standard) is the analytical standard of Nabumetone. This product is intended for research and analytical applications. Nabumetone is an orally active non-acidic anti-inflammatory agent, acts as a potent and selective COX-2 inhibitor, and is the proagent of the active metabolite 6MNA.
  • HY-17485R
    Alminoprofen (Standard)
    		Inhibitor
    Alminoprofen (Standard) is the analytical standard of Alminoprofen. This product is intended for research and analytical applications. Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory agent (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2.
  • HY-N2518R
    Agnuside (Standard)
    		Inhibitor
    Agnuside (Standard) is the analytical standard of Agnuside. This product is intended for research and analytical applications. Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo.
  • HY-131259R
    Ibuprofen Impurity F (Standard)
    		Inhibitor
    Ibuprofen Impurity F (Standard) is the analytical standard of Ibuprofen Impurity F. This product is intended for research and analytical applications. Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
  • HY-N7108R
    7-Hydroxyflavone (Standard)
    		Inhibitor
    7-Hydroxyflavone (Standard) is the analytical standard of 7-Hydroxyflavone. This product is intended for research and analytical applications. 7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. 7-Hydroxyflavone inhibits PKM2 with an IC50 of 2.12 μM. 7-Hydroxyflavone inhibits COX-2 and 5-LOX with IC50 of 27 µg/mL and 33 µg/mL. 7-Hydroxyflavone is orally active.
  • HY-N0149R
    Salicin (Standard)
    		Inhibitor
    Salicin (Standard) is the analytical standard of Salicin. This product is intended for research and analytical applications. Salicin is a natural COX inhibitor.
  • HY-106514
    Prifelone
    		Inhibitor
    Prifelone (R 830; R 830T; S 16820) is a di-tert-butylphenol with anti-inflammatory and antioxidant activity. Prifelone inhibits guinea pig lung oxygenase and bovine seminal vesicle cyclooxygenase.
  • HY-14445R
    FK 3311 (Standard)
    		Inhibitor
    FK 3311 (Standard) is the analytical standard of FK 3311. This product is intended for research and analytical applications. FK 3311 (COX-2 Inhibitor V) is a selective inhibitor of COX-2 with antiinflammatory agent.
  • HY-157578
    COX-2-IN-38
    		Inhibitor
    COX-2-IN-38 (compound 52*) is a potent inhibitor of COX-2, with the IC50 value of 79.4 nM.
  • HY-B1138R
    Fenbufen (Standard)
    		Inhibitor
    Fenbufen (Standard) is the analytical standard of Fenbufen. This product is intended for research and analytical applications. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor.
  • HY-B0227S3
    Ketoprofen-13C6
    		Inhibitor
    Ketoprofen-13C6 (RP-19583-13C6) is 13C labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity.
  • HY-N1996R
    Chebulagic acid (Standard)
    		Inhibitor
    Chebulagic acid (Standard) is the analytical standard of Chebulagic acid. This product is intended for research and analytical applications. Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a M2 serine to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC50 of 9.76 μM.
  • HY-B0531R
    Triflusal (Standard)
    		Inhibitor
    Triflusal (Standard) is the analytical standard of Triflusal. This product is intended for research and analytical applications.
  • HY-W162983
    3,4-Diphenyl-5H-furan-2-one
    		Inhibitor
    3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain.
  • HY-N1500R
    Pulegone (Standard)
    		Inhibitor
    Pulegone (Standard) is the analytical standard of Pulegone (HY-N1500). This product is intended for research and analytical applications. Pulegone is a monoterpene ketone compound widely present in the essential oils of many plants. Pulegone can also be used as a bird repellent. Pulegone has multiple activities such as anti-inflammatory, antibacterial, antifungal, and anti-hyperalgesic effects. Pulegone is particularly effective against bacteria of the Salmonella species.
  • HY-118752R
    Fentiazac (Standard)
    		Inhibitor
    Fentiazac (Standard) is the analytical standard of Fentiazac. This product is intended for research and analytical applications. Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis.
  • HY-108162
    Ataquimast free base
    		Inhibitor
    Ataquimast free base is a COX-2 inhibitor that inhibits the release of leukotrienes, TNF-α and GM-CSF. Ataquimast free base can be used in the study of advanced receptor-positive breast cancer.
  • HY-B1130R
    Isoxicam (Standard)
    		Inhibitor
    Isoxicam (Standard) is the analytical standard of Isoxicam. This product is intended for research and analytical applications. Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis. Isoxicam is a nonselective inhibitor of COX-1 and COX-2.
  • HY-B0253R
    Piroxicam (Standard)
    		Inhibitor
    Piroxicam (Standard) is the analytical standard of Piroxicam. This product is intended for research and analytical applications. Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.