1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N15146
    Aralia-saponin I
    Inhibitor
    Aralia-saponin I is a saponin that can be isolated from Aralia elata, possessing high binding affinity for aerolysin and capable of binding to amino acids critical for aerolysin function. Aralia-saponin I can be utilized in research on infections caused by Aeromonas hydrophila.
    Aralia-saponin I
  • HY-N0716
    Berberine
    Inhibitor
    Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties. The sulfate form (HY-N0716B) improves bioavailability.
    Berberine
  • HY-121785
    10-Thiofolic acid
    Inhibitor
    10-Thiofolic acid is a potent antibacterial and antitumor agent. 10-Thiofolic acid inhibits the growth of Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 7469). 10-Thiofolic acid has the potential for the research of leukemia.
    10-Thiofolic acid
  • HY-N14791
    Amicoumacin C
    Inhibitor
    Amicoumacin C shows moderate activity against bacteria, but does not exhibit any pharmacol activity.
    Amicoumacin C
  • HY-N0368S1
    Linalool-13C3
    Inhibitor
    Linalool-13C3 is 13C labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities.
    Linalool-<sup>13</sup>C<sub>3</sub>
  • HY-W984166
    Antibiotic U 44590
    Inhibitor
    5,6-Dihydro-5-azathymidine has anti-Gram-positive bacteria, negative bacteria and DNA virus activities.
    Antibiotic U 44590
  • HY-N6687R
    Calcimycin (Standard)
    Inhibitor
    N-Desalkylflurazepam (Standard) is the analytical standard of N-Desalkylflurazepam. This product is intended for research and analytical applications. N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC50 values of 55 μM and 37 μM for Cav1.2 and Cav1.3, respectively.
    Calcimycin (Standard)
  • HY-B1355AR
    Oxyphenbutazone (Standard)
    Inhibitor
    Oxyphenbutazone (Standard) is the analytical standard of Oxyphenbutazone. This product is intended for research and analytical applications. Oxyphenbutazone is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis.
    Oxyphenbutazone (Standard)
  • HY-155479
    PqsR-IN-3
    Inhibitor
    PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 μM) and its associated virulence factor pyocyanin (IC50=2.7 μM). PqsR-IN-3 inhibits bacterial biofilm synthesis and is significantly cytotoxic against Pseudomonas aeruginosa. PqsR-IN-3 has synergistic effects with several antibiotics, such as Ciprofloxacin (HY-B0356) and Tobramycin (HY-B0441).
    PqsR-IN-3
  • HY-N8535
    Massarigenin C
    Inhibitor
    Massarigenin C is a compound that can be isolated from Massarina tunicata. Massarigenin C has inhibitory activity against Bacillus subtilis (ATCC 6051).
    Massarigenin C
  • HY-139554AR
    Zifanocycline TFA (Standard)
    Inhibitor
    Zifanocycline (TFA) (Standard) is the analytical standard of Zifanocycline (TFA). This product is intended for research and analytical applications. Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections[1][2].
    Zifanocycline TFA (Standard)
  • HY-B1150R
    Clofoctol (Standard)
    Inhibitor
    Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency.
    Clofoctol (Standard)
  • HY-N14499
    Saframycin H
    Inhibitor
    Saframycin H has the effect of anti-Gram-positive bacteria. Saframycin H has the effect of inhibiting mouse lymphocyte L-1210 with an ID50 of 0.033 μM.
    Saframycin H
  • HY-N15418
    Mikanolide
    Mikanolide is a sesquiterpene that has antibacterial properties. Mikanolide inhibits the growth of Staphylococcus aureus with a zone of 14 mm at a concentration of 100 μg per disk.
    Mikanolide
  • HY-P5603
    Bovine neutrophil beta-defensin 12
    Inhibitor
    Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus.
    Bovine neutrophil beta-defensin 12
  • HY-164128
    AHL modulator-1
    99.15%
    AHL modulator-1 (compound 12) is a modulator of N-acylated L-homoserine lactone (AHL), with the agonism and antagonism of 21% and 42% in cellulase activity and 5% and 32% in potato macerationa, respectively.
    AHL modulator-1
  • HY-B0113S4
    Omeprazole-d3 sodium
    Inhibitor
    Omeprazole-d3 sodium is deuterated labeled Omeprazole (HY-B0113). Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
    Omeprazole-d<sub>3</sub> sodium
  • HY-N15395
    Dermadin
    Inhibitor
    Dermadin is an antibiotic with antibacterial effects.
    Dermadin
  • HY-109755
    PF-04064900
    Inhibitor
    PF-04064900 is a prodrug of sulopenem penem antibiotic.
    PF-04064900
  • HY-126129R
    Desacetylcefotaxime (Standard)
    Inhibitor
    Desacetylcefotaxime (Standard) is the analytical standard of Desacetylcefotaxime. This product is intended for research and analytical applications. Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria.
    Desacetylcefotaxime (Standard)
Cat. No. Product Name / Synonyms Application Reactivity