1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-106760
    FK 089
    Inhibitor
    FK 089 is an antibacterial Agent. FK 089 can be used for the research of infection.
    FK 089
  • HY-170835
    NDM-1 inhibitor-7
    Inhibitor
    NDM-1 inhibitor-7 (Compound A8) is a NDM-1 inhibitor, with IC50 of 10.284 μM. NDM-1 inhibitor-7 restores the ability of MEM to penetrate the cell wall of gram-negative bacteria. NDM-1 inhibitor-7 effectively restores the antibacterial activity of MEM against NDM-1-positive Escherichia coli. NDM-1 inhibitor-7 demonstrates strong efficacy in both the Galleria mellonella infection model and murine peritonitis infection model.
    NDM-1 inhibitor-7
  • HY-N0717S7
    L-Valine-1-13C,15N
    Inhibitor
    L-Valine-1-13C,15N ((S)-Valine-1-13C,15N) is the 13C- and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine-1-<sup>13</sup>C,<sup>15</sup>N
  • HY-119648
    CCR-11
    Inhibitor
    CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents.
    CCR-11
  • HY-N13983
    Arylomycin B4
    Inhibitor
    Arylomycin B4 is a lipohexapeptide antibiotic against Gram-positive bacteria.
    Arylomycin B4
  • HY-162624
    Quorum sensing-IN-5
    Inhibitor
    Quorum sensing-IN-5 is a RpfF-targeted quorum-sensing inhibitor. Quorum sensing-IN-5 inhibits Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC50 values of 9.91 μg/mL and 7.04 μg/mL. Quorum sensing-IN-5 has antimicrobial activity.
    Quorum sensing-IN-5
  • HY-W012088
    (Z)-Methyl tetradec-9-enoate
    Inhibitor
    (Z)-Methyl tetradec-9-enoate (Myristoleic acid methyl ester; Methyl myristoleate) is a cytotoxic component extracted from S. repens fruit extract. It induces apoptosis and necrosis in human prostate cancer LNCaP cells. In addition, (Z)-Methyl tetradec-9-enoate found in cheese-making byproducts inhibits Candida albicans germination with a minimum inhibitory concentration (MIC) of 9 μM in vivo.
    (Z)-Methyl tetradec-9-enoate
  • HY-N14996
    6-Deoxyparomomycin
    Inhibitor
    6-Deoxyparomomycin is found in the strain of Streptomyces rimosus forma paromomycinus with antibacterial activity.
    6-Deoxyparomomycin
  • HY-B1358R
    Lincomycin hydrochloride monohydrate (Standard)
    Inhibitor
    Lincomycin (hydrochloride monohydrate) (Standard) is the analytical standard of Lincomycin (hydrochloride monohydrate). This product is intended for research and analytical applications. Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein.
    Lincomycin hydrochloride monohydrate (Standard)
  • HY-N14011
    Cedarmycin A
    Inhibitor
    Cedarmycin A has activities against Candida, Cryptococcus neoforme and Aspergillus fumigatus, with the MIC values of 12.5-50 μg/mL.
    Cedarmycin A
  • HY-B0724B
    Pazufloxacin
    Inhibitor
    Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia.
    Pazufloxacin
  • HY-N14726
    Primocarcin
    Inhibitor
    Primocarcin is an antibiotic that inhibits Ehrlich ascites cancer.
    Primocarcin
  • HY-173528
    Antimicrobial agent-40
    Inhibitor
    Antimicrobial agent-40 (Compound 5a) has antimicrobial activity against fungi, Gram-negative and Gram-positive bacteria. Antimicrobial agent-40 has good cytotoxicity against MCF-7 cells (IC50: 33.52 μM) and exhibits anticancer activity.
    Antimicrobial agent-40
  • HY-17504AS1
    Rosuvastatin-d6
    Rosuvastatin-d6 (ZD 4522-d6) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
    Rosuvastatin-d<sub>6</sub>
  • HY-13766A
    Timcodar mesylate
    Inhibitor
    Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae.
    Timcodar mesylate
  • HY-163033
    Antitubercular agent-42
    Antitubercular agent-42(19) is a selective fatty acyl-AMP ligase (FAAL) inhibitor (MIC90 = 1.4 µg/mL for M. tuberculosis H37Rv). Antitubercular agent-42 shows antitubercular activity.
    Antitubercular agent-42
  • HY-113718
    DS21412020
    Inhibitor
    DS21412020 is a fluoroquinolone antibacterial agent. DS21412020 inhibits bacterial DNA gyrase (GyrA) and topoisomerase IV, leading to DNA breaks. DS21412020 exhibits significant activity against Gram-positive bacteria such as Staphylococcus aureus (MIC = 0.006 μg/mL), Streptococcus pneumoniae (MIC = 0.05 μg/mL), and Methicillin (HY-121544)-resistant Staphylococcus aureus (MIC = 0.2 μg/mL), and Gram-negative bacteria such as Escherichia coli (MIC = 0.006 μg/mL) and Pseudomonas aeruginosa (MIC = 0.78 μg/mL). DS21412020 significantly reduces bacterial load in mouse pneumonia and MRSA infection models. DS21412020 can be used in the development of next-generation quinolone antibiotics.
    DS21412020
  • HY-141441
    Novobiocic acid
    Novobiocic acid is an aglycone form of the antibiotic Novobiocin (HY-B0425).
    Novobiocic acid
  • HY-B1056R
    Procodazole (Standard)
    Inhibitor
    DTA (Standard) is the analytical standard of DTA. This product is intended for research and analytical applications. DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase.
    Procodazole (Standard)
  • HY-N7115R
    Sultamicillin (Standard)
    Inhibitor
    Sultamicillin (Standard) is the analytical standard of Sultamicillin. This product is intended for research and analytical applications. Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity.
    Sultamicillin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity