2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W722081
    Baumycin C1
    		Inhibitor
    Baumycin C1 is an antitumor antibiotic.
    Baumycin C1
  • HY-N15117
    Polymyxin P1
    		Inhibitor
    Polymyxin P1 is found in Bacillus polymyxa T-39 and can inhibit Gram-positive bacteria.
    Polymyxin P1
  • HY-116271
    Sperabillin C
    		Inhibitor
    Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus.
    Sperabillin C
  • HY-N10617R
    Hygromycin A (Standard)
    		Inhibitor
    Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research.
    Hygromycin A (Standard)
  • HY-17504BS2
    Rosuvastatin-13C,d3 sodium
    Rosuvastatin-13C,d3 sodium is 13C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
    Rosuvastatin-<sub>13</sub>C,d<sub>3</sub> sodium
  • HY-N14530
    Cremeomycin
    		Inhibitor
    Cremeomycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremeomycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro.
    Cremeomycin
  • HY-123779
    RWJ-49815
    		Inhibitor
    RWJ-49815 is a histidine kinase inhibitor (IC50 = 1.6 uM). RWJ-49815 inhibits the autophosphorylation of kinase A in the KinA-Spo0F two-component signal transduction system in vitro. RWJ-49815 inhibits the growth of bacteria such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus pneumoniae. RWJ-49815 also inhibits the growth of Fungal such as Saccharomyces cerevisiae and Candida albicans.
    RWJ-49815
  • HY-N13966
    Pyralomicin 2a
    		Inhibitor
    Pyralomicin 2a is an antibiotic with antibacterial activity.
    Pyralomicin 2a
  • HY-N12164
    Linearmycin B
    		Inhibitor
    Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively.
    Linearmycin B
  • HY-W040271
    N-3-Hydroxydecanoyl-DL-homoserine lactone
    		Inhibitor
    N-3-Hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule. N-3-Hydroxydecanoyl-DL-Homoserine lactone activates the transcription factor SdiA (EC50 = 0.6 µM), which detects N-acyl homoserine lactones (AHLs), and exerts its effect in Salmonella enterica (S. enterica)12.
    N-3-Hydroxydecanoyl-DL-homoserine lactone
  • HY-116943
    MTC420
    		Inhibitor
    MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM).
    MTC420
  • HY-119201
    PNU-140457
    		Inhibitor
    PNU-140457 is an antibacterial agent targeting 30S ribosomal subunit. PNU-140457 is promising for research of bacterial Infections.
    PNU-140457
  • HY-169818
    Keto lovastatin
    		Inhibitor
    Keto lovastatin is an impurity of Lovastatin (HY-N0504) with antibacterial activity. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
    Keto lovastatin
  • HY-N14998
    Damavaricin D
    		Inhibitor
    Damavaricin D has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-fungal effects.
    Damavaricin D
  • HY-N14046
    Celesticetin B
    		Inhibitor
    Celesticetin B is an antibiotic. Celesticetin B is mainly antibacterial against Gram-positive microorganisms.
    Celesticetin B
  • HY-N14538
    Saframycin E
    		Inhibitor
    Saframycin E has the effect of anti-Gram-positive bacteria. Saframycin B also has weak activity against mycobacteria.
    Saframycin E
  • HY-13777S
    Zoledronic acid-d5
    Zoledronic acid-d5 is deuterated labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
    Zoledronic acid-d<sub>5</sub>
  • HY-N1190
    DL-Syringaresinol
    		Inhibitor
    DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv.
    DL-Syringaresinol
  • HY-N14310
    Hongoquercin A
    		Inhibitor
    Hongoquercin A is a sesquiterpene antibiotic. Hongoquercin A has moderate anti-Gram-positive bacteria activity with a MIC of 4-8 μg/mL.
    Hongoquercin A
  • HY-158980
    Antifungal agent 103
    		Inhibitor
    Antifungal agent 103 (compound 7y) is a potent antifungal agent. Antifungal agent 103 inhibits R. solani with an EC50 of 0.47 μg/mL.
    Antifungal agent 103
Cat. No. Product Name / Synonyms Application Reactivity