2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14237
    Epoxyquinomicin A
    		Inhibitor
    Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 µg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 µg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis.
    Epoxyquinomicin A
  • HY-163843
    Antibacterial agent 234
    		Inhibitor
    Antibacterial agent 234 (6p) is an antibacterial agent. Antibacterial agent 234 (6p) exhibits good activity against Klebsiella pneumoniae with a MIC value of 6.25 µg/mL.
    Antibacterial agent 234
  • HY-B0656AS3
    Rabeprazole-13C,d3 sodium
    Rabeprazole-13C,d3 (sodium) (LY307640-13C,d3 (sodium)) is 13C labeled Rabeprazole (sodium). Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-<sup>13</sup>C,d<sub>3</sub> sodium
  • HY-N15061
    Naphthomycin A
    		Inhibitor
    Naphthomycin A has the effect of anti Gram-positive bacteria and fungi, and inhibits the synthesis of fatty acids by coliform bacteria.
    Naphthomycin A
  • HY-N14507
    Mycinamicin VII
    		Inhibitor
    Mycinamicin VII is a macrolide antibiotic. Mycinamicin VII shows activity against Gram-positive bacteria.
    Mycinamicin VII
  • HY-121104A
    Bactobolin hydrochloride
    		Inhibitor
    Bactobolin hydrochloride (Compound 1) is an antibiotic, which inhibits Escherichia coli, Salmonella, Shigella, Staphylococcus and Bacillus subtilis, with MICs of 0.3-6.25 μg/mL. Bactobolin hydrochloride exhibits antitumor efficacy against leukemia, with a LD50 value of 6.25-12.5 mg/kg.
    Bactobolin hydrochloride
  • HY-B0226A
    (E)-Nitrofurazone
    		Inhibitor
    (E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery.
    (E)-Nitrofurazone
  • HY-N14652
    Glycocinnasperimicin D
    		Inhibitor
    Glycocinnasperimicin D is a glycoside cinnamyl imide histamine antibiotic. Glycocinnasperimicin D has the activity of anti-Gram positive bacteria and negative bacteria. Glycocinnasperimicin D inhibits leukemia L1210 cell with an IC50 of 2.0 μg/mL.
    Glycocinnasperimicin D
  • HY-B0330DR
    (R)-Ofloxacin (Standard)
    		Inhibitor
    (R)-Ofloxacin (Standard) is the analytical standard of (R)-Ofloxacin (HY-B0330D). (R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone antibiotic. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria.
    (R)-Ofloxacin (Standard)
  • HY-119626
    Dihydrodaunomycin
    		Inhibitor
    Dihydrodaunomycin has antibacterial and antitumor activities.
    Dihydrodaunomycin
  • HY-126046
    ACP1b
    		Inhibitor
    ACP1b is an activator for ClpP protease with Kd of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL.
    ACP1b
  • HY-N14955
    3-O-α-D-Forosaminyl-(+)-griseusin
    		Inhibitor
    3-O-α-D-Forosaminyl-(+)-griseusin is a memberof naphthoquinone antibiotic. 3-O-α-D-Forosaminyl-(+)-griseusin is active against Gram-positive bacteria including methicillin-resistant strain of Staphylococcus aureus (MRSA).
    3-O-α-D-Forosaminyl-(+)-griseusin
  • HY-127020
    Deoxyenterocin
    Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 μg/mL. Deoxyenterocin (50 μg/mL) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 μM.
    Deoxyenterocin
  • HY-115159
    Ro 14-9578
    		Inhibitor
    Ro 14-9578 is a tricyclic quinolone analog with antibacterial activity. Ro 14-9578 inhibits DNA biosynthesis (IC50=117 μM) and DNA supercoiling (IC50=66.8 μM) in Escherichia coli. Furthermore, Ro 14-9578 exhibits inhibitory effects against various Gram-negative bacteria and Staphylococcus aureus.
    Ro 14-9578
  • HY-N14315
    Ochracenomicin A
    		Inhibitor
    Ochracenomicin A has a strong effect against Gram-positive bacteria (including MRSA strain), and also against Gram-negative bacteria and candida albicans.
    Ochracenomicin A
  • HY-N14684
    Griseusin B
    		Inhibitor
    Griseusin B is a quinone antibiotic. Griseusin B mainly has anti-Gram-positive bacterial activity.
    Griseusin B
  • HY-123190
    Safracin A
    		Inhibitor
    Safracin A has anti-Gram-positive bacteria, Gram-negative bacteria and anti-tumor effect.
    Safracin A
  • HY-W441968
    L-threo-β-Hydroxyaspartic acid
    		Inhibitor
    L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic. L-threo-β-Hydroxyaspartic acid has the activity of inhibiting Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei and Botrytis cinerea.
    L-threo-β-Hydroxyaspartic acid
  • HY-N14678
    Piloquinone
    Piloquinone is a phenanthrene compound. Piloquinone has inhibitory effect on mycobacterium and protozoa, but the effect is not strong.
    Piloquinone
  • HY-17516R
    Tolfenpyrad (Standard)
    		Inhibitor
    Tolfenpyrad (Standard) is the analytical standard of Tolfenpyrad (HY-17516). This product is intended for research and analytical applications. Tolfenpyrad is an orally active insecticide, acaricide and antibacterial agent. Tolfenpyrad inhibits Complex I in the mitochondrial respiratory electron transport chain, interfering with the cell respiration process. Tolfenpyrad has significant insecticidal activity against a variety of insect pests such as H. contortus, Coccinella septempunctata. Tolfenpyrad has antibacterial activity against Francisella novicida, with an IC50 of 1.2 µM or 1.5 µM.
    Tolfenpyrad (Standard)
Cat. No. Product Name / Synonyms Application Reactivity