1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N10572
    Antibacterial synergist 2
    Inhibitor
    Antibacterial synergist 2 (compound 27) is a biofilm inhibitor. Antibacterial synergist 2 shows inhibitory effects to S. enterica, S. aureus, P. aeruginosa and C. albicans. Antibacterial synergist 2 can be used for the research related to biofilm-forming pathogens.
    Antibacterial synergist 2
  • HY-138145
    8-Acetyl-7-hydroxycoumarin
    Inhibitor
    8-Acetyl-7-hydroxycoumarin is a coumarin-like compound found in Mexican patchouli (Tagetes lucida) that has anti-bacterial and anti-fungal activities.
    8-Acetyl-7-hydroxycoumarin
  • HY-N7699F
    D-Octamannuronic acid
    Inhibitor
    D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia.
    D-Octamannuronic acid
  • HY-157482
    EBP-59
    Inhibitor
    EBP-59 is a bacterial inhibitor with antibiofilm activity against Gram-positive bacteria. EBP-59 is effective against Staphylococcus aureus and MRSA (methicillin–resistant staphylococcus aureus). EBP-59 can be used to study bacterial infections.
    EBP-59
  • HY-128502
    Nifurtoinol
    Inhibitor
    Nifurtoinol is a nitrofuran-derivative antibiotic with antibacterial effects. Nifurtoinol can be used for the research of urinary tract infections.
    Nifurtoinol
  • HY-144621
    Antibacterial agent 75
    Inhibitor
    Antibacterial agent 75 (compound 24) is an antibacterial agent. Antibacterial agent 75 (compound 24) is able to re-sensitize VRSA to vancomycin.
    Antibacterial agent 75
  • HY-P10219
    Brevicidine analog 22
    Inhibitor
    Brevicidine analog 22 (22) exerts broad spectrum antimicrobial activity and excellent stability (t1/2 = 40.98 h), with MICs of 2-16 μM for gram-negative and gram-positive bacteria.
    Brevicidine analog 22
  • HY-133726R
    Bixafen (Standard)
    Inhibitor
    Bixafen (Standard) is the analytical standard of Bixafen. This product is intended for research and analytical applications. Bixafen, a member of the pyrazole class of fungicides, serves as a broad-spectrum agent for controlling pathogens in cereal crops by functioning as a succinate dehydrogenase inhibitor.
    Bixafen (Standard)
  • HY-156123
    DHFR-IN-9
    Inhibitor
    DHFR-IN-9 (compound 8A) is a dihydrofolate reductase (DHFR) inhibitor that affects purine and thymidylate biosynthesis in cell proliferation and growth. DHFR-IN-9 inhibits methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 (IC50=0.25 μg/mL) and has anti-infective effects in mouse models of systemic infection and thigh infection caused by it (dose: 2.5 mg /kg, 5 mg/kg; ip). DHFR-IN-9 has stronger anticancer activity than paclitaxel (Y-B0015) in a mouse model of breast cancer (dose: 2.5 mg/kg; ip; once every 3 days).
    DHFR-IN-9
  • HY-W749665
    Clindamycin Hydrochloride-13C,d3
    Clindamycin Hydrochloride-13C,d3 is the deuterium and 13C-labeled Clindamycin hydrochloride (HY-B0408A). Clindamycin hydrochloride is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
    Clindamycin Hydrochloride-<sup>13</sup>C,d<sub>3</sub>
  • HY-W707099
    Ro 20-0657/000-d3
    Ro 20-0657/000-d3 is the deuterium labeled Ro 20-0657/000 (HY-100622). Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.
    Ro 20-0657/000-d<sub>3</sub>
  • HY-N1079
    Vitexilactone
    Activator
    Vitexilactone is a diterpenoid that can be isolated from the leaves of Vitex negundo L. Vitexilactone shows antimicrobial activity towards E. coli. Vitexilactone induces cell apoptosis and inhibits cell cycle of cancer cells. Vitexilactone can be used for the research of cancer.
    Vitexilactone
  • HY-N6777R
    Penicillic acid (Standard)
    Inhibitor
    Tetracaine (hydrochloride) (Standard) is the analytical standard of Tetracaine (hydrochloride). This product is intended for research and analytical applications. Tetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is mainly used topically in ophthalmology and as an antipruritic.
    Penicillic acid (Standard)
  • HY-19581
    Baquiloprim
    Inhibitor
    Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria.
    Baquiloprim
  • HY-N0656AR
    (+)-Usnic acid (Standard)
    Inhibitor
    (+)-Usnic acid (Standard) is the analytical standard of (+)-Usnic acid. This product is intended for research and analytical applications. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium.
    (+)-Usnic acid (Standard)
  • HY-N4157R
    Isopteropodine (Standard)
    Inhibitor
    Isopteropodine (Standard) is the analytical standard of Isopteropodine (HY-N4157). This product is intended for research and analytical applications. Isopteropodine is a positive modulator that selectively acts on muscarinic M1 and 5-HT2 receptors. Isopteropodine has an EC50 of 9.92 μM for acetylcholine and 14.5 μM for 5-HT. Isopteropodine also has antibacterial activity against Gram-positive bacteria, with MICs of 150 μg/mL and 250 μg/mL for Staphylococcus aureus and Bacillus subtilis, respectively. Isopteropodine enhances receptor function by increasing the affinity of agonists for receptors and can also inhibit the growth of specific Gram-positive bacteria, and can be used in cognitive impairment and antibacterial research.
    Isopteropodine (Standard)
  • HY-125445
    PCTR1
    Inhibitor
    PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs).
    PCTR1
  • HY-147429A
    Zosurabalpin TFA
    Inhibitor
    Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport.
    Zosurabalpin TFA
  • HY-151552
    Mtb-cyt-bd oxidase-IN-5
    Inhibitor
    Mtb-cyt-bd oxidase-IN-5 (compound 1k) is a Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.37 μM. Mtb-cyt-bd oxidase-IN-5 can effectively inhibit the growth of Mtb (MIC= 256 μM). Mtb-cyt-bd oxidase-IN-5 can be used in the study of tuberculosis.
    Mtb-cyt-bd oxidase-IN-5
  • HY-N8089
    Bis(dihydrochelerythrinyl)amine
    Inhibitor
    Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.
    Bis(dihydrochelerythrinyl)amine
Cat. No. Product Name / Synonyms Application Reactivity