1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-119502R
    Camalexin (Standard)
    Inhibitor
    Camalexin (Standard) is the analytical standard of Camalexin. This product is intended for research and analytical applications. Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3].
    Camalexin (Standard)
  • HY-15460R
    CHIR-090 (Standard)
    Inhibitor
    CHIR-090 (Standard) is the analytical standard of CHIR-090. This product is intended for research and analytical applications. CHIR-090 is a potent, slow, tight-binding inhibitor of the LpxC deacetylase. It binds to E. coli LpxC with a Ki of 4.0 nM. CHIR-090 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CHIR-090 (Standard)
  • HY-100381R
    Nigericin sodium salt (Standard)
    Inhibitor
    Nigericin (sodium salt) (Standard) is the analytical standard of Nigericin (sodium salt). This product is intended for research and analytical applications. Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC.
    Nigericin sodium salt (Standard)
  • HY-P3417
    Amp1EP9
    Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections.
    Amp1EP9
  • HY-42649
    NSC 14699
    Inhibitor 99.64%
    NSC 14699 is a small molecule non-peptide inhibitor of botulinum neurotoxin serotype E. NSC 14699 is promising for research of therapeutic and cosmetic agents.
    NSC 14699
  • HY-P5731
    Bac7(1-35)
    Inhibitor
    Bac7(1-35) is a proline-rich antimicrobial peptide, selective for Gram-negative bacteria, which acts intracellularly after membrane translocation.
    Bac7(1-35)
  • HY-161823
    Anti-MRSA agent 13
    Inhibitor
    Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated MRSA strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to MRSA death through multi-target synergies.
    Anti-MRSA agent 13
  • HY-P5256
    Oligopeptide-20
    Inhibitor
    Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient.
    Oligopeptide-20
  • HY-P2483
    Octaarginine
    Inhibitor
    Octaarginine is a cell-penetrating peptide (CPP). CPPs show membrane translocation activities. CPPs are used for intracellular delivery of various membrane-impermeable bioactive agents because of their intrinsic ability to gain access to cell interiors. CPPs have also been used to deliver antibacterial agents to target intracellular bacteria.
    Octaarginine
  • HY-W768895
    Sanguinarine chloride-13C,d3
    Sanguinarine chloride-13C,d3 (Sanguinarin chloride-13C,d3) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine chloride-<sup>13</sup>C,d<sub>3</sub>
  • HY-10844S1
    Pretomanid-d5
    Inhibitor
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d<sub>5</sub>
  • HY-N3199
    Neorauflavene
    Inhibitor
    Neorauflavene is a phenolic neorautanenia isoflavanoid isolated from Neorautanenia edulis. Neorauflavene shows antibacterial activities against E. faecalis, S. suis, S. agalactiae, P. aeruginosa, B. subtilis, and R. anatipestifer.
    Neorauflavene
  • HY-162898
    Anti-virulence factor-IN-1
    Inhibitor
    Anti-virulence factor-IN-1 (Compound 4S) is a bacterial virulence factor inhibitor by interfering with the bacterial infection process. Anti-virulence factor-IN-1 exhibits an antibacterial activity against Xoo in vitro with an EC50 value of 0.28 µg/mL. Anti-virulence factor-IN-1 can be used to effectively manage rice bacterial leaf blight in vivo. Anti-virulence factor-IN-1 is promising for research of plant bacterial disease.
    Anti-virulence factor-IN-1
  • HY-151941
    MtInhA-IN-1
    Inhibitor
    MtInhA-IN-1 is a selective and orally active Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhibitor with an IC50 of 0.23 μM. MtInhA-IN-1 potently against M. tuberculosis H37Rv strain with a MIC value of 0.4 μM.
    MtInhA-IN-1
  • HY-B0289S2
    Erdosteine-d4
    Erdosteine-d4 is a deuterium labeled Erdosteine (HY-B0289). Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects.
    Erdosteine-d<sub>4</sub>
  • HY-168648
    DNA Gyrase/DHFR-IN-1
    Inhibitor
    DNA Gyrase/DHFR-IN-1 is a dual inhibitor of bacterial DNA gyrase and DHFR, with IC50s of 182 μM and 3.90 μM for E. coli DNA gyrase and DHFR respectively. DNA Gyrase/DHFR-IN-1 has bactericidal and antifungal activity.
    DNA Gyrase/DHFR-IN-1
  • HY-151918
    Antibacterial agent 125
    Inhibitor 98.90%
    Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance.
    Antibacterial agent 125
  • HY-N0401AS
    (Z)-Ligustilide-d7
    Inhibitor
    (Z)-Ligustilide-d7 is the deuterium-labeled (Z)-Ligustilide (HY-N0401A).
    (Z)-Ligustilide-d<sub>7</sub>
  • HY-B1213AS
    Trimipramine-d3 (N-methyl-d3) maleate
    Trimipramine-d3 (N-methyl-d3) (maleate) is the deuterium labeled Trimipramine (N-methyl) maleate.
    Trimipramine-d<sub>3</sub> (N-methyl-d<sub>3</sub>) maleate
  • HY-P2087
    Bassianolide
    Inhibitor
    Bassianolide is a cyclooligomer depsipeptide secondary metabolite. Bassianolide is an insecticidal virulence factor of Beauveria bassiana. Bassianolide inhibits acetylcholine-induced smooth muscle contraction, and shows moderate antiplasmodial and anti-mycobacterial activities.
    Bassianolide
Cat. No. Product Name / Synonyms Application Reactivity