1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W004282R
    Undecanoic acid (Standard)
    Inhibitor 99.83%
    Undecanoic acid (Standard) (Undecanoate (Standard)) is the analytical standard of Undecanoic acid (HY-W004282). This product is intended for research and analytical applications. Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid (Standard)
  • HY-152136
    Antituberculosis agent-6
    Inhibitor
    Antituberculosis agent-6 (compound 9g) is a potent antimycobacterial agent. Antituberculosis agent-6 shows significant activity against M. tuberculosis, with a MIC of 3.49 μM. Antituberculosis agent-6 also shows good antifungal activity against A. niger, with a MIC of 62.50 μM. Antituberculosis agent-6 shows high GI absorption.
    Antituberculosis agent-6
  • HY-B0200BS
    Cephalexin-d5 monohydrate
    Inhibitor
    Cephalexin-d5 (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al.
    Cephalexin-d<sub>5</sub> monohydrate
  • HY-13777AR
    Zoledronic acid monohydrate (Standard)
    Zoledronic acid (monohydrate) (Standard) is the analytical standard of Zoledronic acid (monohydrate). This product is intended for research and analytical applications. Zoledronic acid monohydrate (Zoledronate monohydrate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic acid monohydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic acid monohydrate also has anti-cancer effects.
    Zoledronic acid monohydrate (Standard)
  • HY-151160
    LasR-IN-1
    Inhibitor
    LasR-IN-1 (compound 9g) is a potent LasR inhibitor. LasR-IN-1 has good efficacy toward E. coli. LasR-IN-1 shows anti-bacterial activity, with a MIC of 28.13 μM against P. aeruginosa.
    LasR-IN-1
  • HY-P6172
    GCO-(GPO)10-GCOG
    Inhibitor
    GCO-(GPO)10-GCOG is a GPO repeat-containing peptide with a single collagen triple helix structure similar to collagen. The cross-linked triple helix GCO-(GPO)10-GCOG can form a collagen-related peptide (CRP) mimetic that tightly binds to the Yersinia adhesin YadA. YadA mediates the adhesion of the human enteric pathogen Yersinia enterocolitica to collagen and other extracellular matrix components, potentially interfering with host processes mediated by endogenous collagen-binding proteins in vivo. GCO-(GPO)10-GCOG can be used to study YadA-associated infections.
    GCO-(GPO)10-GCOG
  • HY-162923
    Antibacterial agent 244
    Inhibitor
    Antibacterial agent 244 is an orally active compound with broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria, with a MIC value of 1–4 μg/mL and low hemolytic toxicity (HC50 of 111.6 μg/mL). Antibacterial agent 244 disrupts bacterial transmembrane potential, increases membrane permeability, leading to leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. Antibacterial agent 244 can be used in research related to Gram-positive bacterial infections.
    Antibacterial agent 244
  • HY-137502
    ML267
    Inhibitor
    ML267 a potent Sfp phosphopantetheinyl transferase (PPTases) inhibitor with an IC50 of 0.29 μM. ML267 also inhibits AcpS-PPTase with an IC50 of 8.1 μM. ML267 possesses specific Gram-positive-targeted bactericidal activities.
    ML267
  • HY-139778
    Antibacterial agent 61
    Inhibitor
    Antibacterial agent 61 (example 27) is a antibacterial agent (extracted from patent WO2013030735A1).
    Antibacterial agent 61
  • HY-135752
    Carbendazim mixture with flusilazole
    Inhibitor
    Carbendazim mixture with flusilazole is a fungicide used to control sooty mold caused by Botrytis narcissicola. The disease is the most common foliar disease of daffodils (Narcissus cultivars) in the UK and causes significant losses in bulb and flower production. Carbendazim mixture with flusilazole was found to be effective in reducing lesion size and significantly reducing symptoms of secondary sooty mold after spraying when used in combination with several other fungicides. In field trials in Cambridgeshire and Lincolnshire, a spraying program using this fungicide mixture was effective in controlling sooty mold. In addition, alternating four to six sprays using two or three fungicides with different modes of action not only reduced disease damage but also increased bulb production. The study discusses the selection of appropriate fungicides and control methods that may reduce the number of spraying applications.
    Carbendazim mixture with flusilazole
  • HY-W738271
    Veratryl alcohol-13C
    Veratryl alcohol-13C (3,4-Dimethoxybenzyl alcohol-13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy.
    Veratryl alcohol-<sup>13</sup>C
  • HY-139987
    LeuRS-IN-1
    Inhibitor
    LeuRS-IN-1 is a potent, orally active M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS) inhibitor. LeuRS-IN-1 has IC50 and Kd values of 0.06 μM, 0.075 μM for M.tb LeuRS, respectively. LeuRS-IN-1 inhibits human cytoplasmic LeuRS (IC50=38.8 μM), and HepG2 protein synthesis (EC50=19.6 μM).
    LeuRS-IN-1
  • HY-108879
    Cefotetan disodium
    Inhibitor
    Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis.
    Cefotetan disodium
  • HY-N10087A
    Angustifoline hydrochloride
    Inhibitor
    Angustifoline hydrochloride, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline hydrochloride exhibits antimicrobial activity. Angustifoline hydrochloride could have bacteriostatic effects against S. aureusB. subtilisE. coliP. aeruginosa and B. thuringiensis.
    Angustifoline hydrochloride
  • HY-N5113
    6α-Chloro-5β-hydroxywithaferin A
    6α-Chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties.
    6α-Chloro-5β-hydroxywithaferin A
  • HY-144728
    MraY-IN-3 hydrochloride
    Inhibitor
    MraY-IN-1 (compound 12a) is a potent  MraY inhibitor with an IC50 value of 140 μM. MraY-IN-1 has antimicrobial activity against Escherichia coli K12, Bacillus subtilis W23 and Pseudomonas fluorescens Pf-5 with MIC50s of 7 µg/mL, 12 µg/mL and 46 µg/mL, respectively. MraY-IN-1 can be used for researching anti-bacteria.
    MraY-IN-3 hydrochloride
  • HY-P5613
    XT-1
    Inhibitor
    XT-1 is an antimicrobial peptide derived from skin secretions of Xenopus tropicalis. XT-1 has strong activity against S.aureus, E.coli and C.albicans, the vaule of MIC are 5, 6, 50 μM , respectively.
    XT-1
  • HY-B0213S
    Sulfameter-d4
    Inhibitor
    Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections.
    Sulfameter-d<sub>4</sub>
  • HY-155250
    Antibacterial agent 154
    Inhibitor
    Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent. Antibacterial agent 154 inhibits Gram-positive and Gram-negative bacteria. Antibacterial agent 154 demonstrated in vivo efficacy in a mouse model of staphylococcal sepsis.
    Antibacterial agent 154
  • HY-113601
    Linatine
    Inhibitor
    Linatine is an antagonist for Vitamin B6 (HY-150525). Linatine inhibits the growth of chicken and Azotobacter vinelandii, induces vitamin B6 deficiency symptoms in chickens.
    Linatine
Cat. No. Product Name / Synonyms Application Reactivity