1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-163197
    JSF-2827
    Inhibitor
    JSF-2827 is a benzothiophene with antibacterial activity against Enterococcus faecium.
    JSF-2827
  • HY-151614
    Anti-infective agent 7
    Inhibitor
    Anti-infective agent 7 is a potent anti-infectious agent. Anti-infective agent 7 has anti-infection activity against P. falciparum (IC50=2.5 μM) and M. tuberculosis (MIC=9 μM).
    Anti-infective agent 7
  • HY-W436428
    V-161
    Inhibitor
    V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 µg/mL and 4 µg/mL. V-161 inhibits colonization of VRE in mouse small intestine.
    V-161
  • HY-149811
    AcrB-IN-3
    Inhibitor
    Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
    AcrB-IN-3
  • HY-P5576
    Aurein 3.3
    Inhibitor
    Aurein 3.3 is an antibiotic antimicrobial peptide. Aurein 3.3 also has anticancer activity.
    Aurein 3.3
  • HY-152495
    MenA-IN-1
    Inhibitor
    MenA IN-1 is an effective inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB) with an IC50 value of 13 µM and an GIC50 value of 8 µM. MenA IN-1 can be used to curb the continuous spread of tuberculosis.
    MenA-IN-1
  • HY-100821
    2,4-Dihydroxyphenylacetylasparagine
    Inhibitor
    2,4-Dihydroxyphenylacetylasparagine is a potent and selective antagonist of glutamate. 2,4-Dihydroxyphenylacetylasparagine inhibits glutamate binding to rat brain synaptic membranes.
    2,4-Dihydroxyphenylacetylasparagine
  • HY-N2805
    9-Oxonerolidol
    Inhibitor
    9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic.
    9-Oxonerolidol
  • HY-B0712S1
    Ceftriaxone-13C2,d3 triethylammonium salt
    Inhibitor
    Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis.
    Ceftriaxone-<sup>13</sup>C<sub>2</sub>,d<sub>3</sub> triethylammonium salt
  • HY-121071
    Ascamycin
    Inhibitor
    Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively.
    Ascamycin
  • HY-B1436S
    Nifuroxazide-d4
    Inhibitor
    Nifuroxazide-d4 is the deuterium labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
    Nifuroxazide-d<sub>4</sub>
  • HY-147000
    DNA Gyrase-IN-1
    Inhibitor
    DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis (Mtb) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis.
    DNA Gyrase-IN-1
  • HY-157808
    Antibacterial agent 185
    Inhibitor
    Antibacterial agent 185 (compound IP-01) is a potent antibacterial agent. Antibacterial agent 185 inhibits filamentous temperature-sensitive mutant Z (FtsZ) polymerization and bundling by increasing GTP hydrolysis. Antibacterial agent 185 inhibits Streptococcus pneumoniae and shows narrow-spectrum activity.
    Antibacterial agent 185
  • HY-N0540R
    Cynaroside (Standard)
    Inhibitor
    Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. Cynaroside also is a promising inhibitor for H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities.
    Cynaroside (Standard)
  • HY-147777
    14α-Demethylase/DNA Gyrase-IN-2
    Inhibitor
    14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities.
    14α-Demethylase/DNA Gyrase-IN-2
  • HY-146301
    Mt KARI-IN-5
    Inhibitor
    Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 4.72 μM. Mt KARI-IN-5 has inhibitory activity against Mtb H37Rv (MIC = 1.56 μM) and low cytotoxicity (HEK IC50 > 64 μg/mL)
    Mt KARI-IN-5
  • HY-N8186
    (3R)-7,4’-Dihydrohomoisoflavanone
    Inhibitor
    (3R)-7,4’-Dihydrohomoisoflavanone is a natural product with antibacterial activities against S. aureus and methicillin-resistant Staphylococcus aureus (MRSA).
    (3R)-7,4’-Dihydrohomoisoflavanone
  • HY-163505
    Anti-MRSA agent 11
    Inhibitor
    Anti-MRSA agent 11 suppresses fluoroquinolone-sensitive strain USA500 and -resistant MRSA isolate Mu50 (MIC =0.39 μg/mL). Anti-MRSA agent 11 displayes favorable in vivo half-life and safety profiles.
    Anti-MRSA agent 11
  • HY-19487A
    Ribocil B
    Inhibitor
    Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
    Ribocil B
  • HY-P5662
    Brevinin-2EC
    Brevinin-2EC is an antimicrobial peptide derived from the skin secretions of Rana esculenta.
    Brevinin-2EC
Cat. No. Product Name / Synonyms Application Reactivity