1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-163104
    Antibacterial agent 169
    Inhibitor
    Antibacterial agent 169 (Compound 28) is a pyrrolamide-type GyrB/ParE inhibitor with antibacterial activity. Antibacterial agent 169 has an inhibitory effect on Gyrase and Topo IV of Staphylococcus aureus, with IC50 values of 49 nmol/L and 1.513 μmol/L respectively.
    Antibacterial agent 169
  • HY-P2047
    Lavendomycin
    Inhibitor
    Lavendomycin is a peptide antibiotic from Streptomyces. Lavendomycin inhibits Gram-positive bacteria.
    Lavendomycin
  • HY-143326
    Antibacterial agent 83
    Inhibitor
    Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes.
    Antibacterial agent 83
  • HY-151458
    VEGFR-2/DHFR-IN-1
    Inhibitor
    VEGFR-2/DHFR-IN-1 (compound 8b) is an inhibitor of VEGFR-2 and DHFR with IC50s of 0.384 and 7.881 μM, respectively. VEGFR-2/DHFR-IN-1 shows good antibacterial activities against Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA and MRSA with MIC values of 16, 16, 16, 8, and 16 μg/mL, respectively. VEGFR-2/DHFR-IN-1 exhibits good cytotoxic activities against C26, HepG2, and MCF7 cancer cell lines with IC50 values of 2.97-7.12 μM. VEGFR-2/DHFR-IN-1 can be used for the research of cancer.
    VEGFR-2/DHFR-IN-1
  • HY-B0220R
    Erythromycin (Standard)
    Inhibitor
    Erythromycin (Standard) is the analytical standard of Erythromycin. This product is intended for research and analytical applications. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research.
    Erythromycin (Standard)
  • HY-131478
    Pyruvic acid semicarbazone
    Inhibitor
    Pyruvic acid semicarbazone is an inhibitor of bacterial and fungal. Pyruvic acid semicarbazone is promising for research of anti-infective agents, anti-tumor therapies, and plant growth regulation.
    Pyruvic acid semicarbazone
  • HY-144701R
    SABA1 (Standard)
    Inhibitor
    Fluopicolide (Standard) is the analytical standard of Fluopicolide. This product is intended for research and analytical applications. Fluopicolide is the active compound.
    SABA1 (Standard)
  • HY-151280
    Antifungal agent 37
    Inhibitor
    Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity.
    Antifungal agent 37
  • HY-124814
    C215
    99.63%
    C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages.
    C215
  • HY-162672
    Antibacterial agent 231
    Inhibitor
    Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs). Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance.
    Antibacterial agent 231
  • HY-113795
    Aldgamycin E
    Inhibitor
    Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity.
    Aldgamycin E
  • HY-P10814
    MciZ (B. subtilis)
    Inhibitor
    MciZ (B. subtilis), a 40-amino-acid peptide, inhibits the GTPase activity of FtsZ that prevents inappropriate Z-ring formation during sporulation.
    MciZ (B. subtilis)
  • HY-158320
    T3SS-IN-5
    T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS). T3SS-IN-5 reduces bacterial pathogenicity without affecting bacterial viability by inhibiting the expression of genes associated with T3SS.
    T3SS-IN-5
  • HY-117990
    GSK572A
    Inhibitor
    GSK572A is a potent EchA6 inhibitor with an Kd value of 1.9 µM. GSK572A shows anti-tubercular activity.
    GSK572A
  • HY-174219
    BT-33
    Inhibitor
    BT-33 is a fuorinated macrobicyclic oxepanoprolinamide antibiotic with broad-spectrum activity against multidrug-resistant bacterial pathogens.
    BT-33
  • HY-134947
    11-Hydroxynovobiocin
    Inhibitor
    11-Hydroxynovobiocin has anti-Gram-negative bacteria effect.
    11-Hydroxynovobiocin
  • HY-146165
    Metallo-β-lactamase-IN-8
    Inhibitor
    Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity.
    Metallo-β-lactamase-IN-8
  • HY-151960
    Antitubercular agent-36
    Inhibitor
    Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis.
    Antitubercular agent-36
  • HY-144721
    Antitubercular agent-11
    Antitubercular agent-11 (Compound 1e) is an antitubercular agent. Antitubercular agent-11 with a bulkier electron-donating group (Bu-t) demonstrated the best MIC value of 0.060 μg/mL.
    Antitubercular agent-11
  • HY-17358S1
    Loteprednol Etabonate-d3
    Inhibitor
    Loteprednol Etabonate-d3 is the deuterium labeled Loteprednol Etabonate. Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.
    Loteprednol Etabonate-d<sub>3</sub>
Cat. No. Product Name / Synonyms Application Reactivity