Cholinesterase (ChE)

Cholinesterase (ChE) Related Products (478):

By Effects:	Inhibitors (388) Controls (4) Agonists (3) Antagonists (6) Activators (22) Modulators (3) Inducer (1)

Cat. No.	Product Name	Effect	Purity

HY-Y0320

Dimethyl sulfoxide, meets analytical specification of Ch.P.	Inhibitor	99.99%
Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties. MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-Y0320C

Dimethyl sulfoxide	Inhibitor	99.98%
Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-101981

Uridine 5'-monophosphate	Activator	99.98%
Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

HY-125854

Phosphatidylcholines, egg	Inhibitor	99.79%
Phosphatidylcholines, egg are a type of phosphatidylcholine that can be isolated and extracted from eggs, primarily present in egg yolks. As a major phospholipid component of cell membranes, Phosphatidylcholines, egg play a key role in providing nutrition and protection to the body. Phosphatidylcholines, egg can inhibit oxidative stress and neurotoxicity, exerting neuroprotective effects. Additionally, Phosphatidylcholines, egg can suppress the lymphatic absorption of cholesterol in the intestine and are also used in research on intestinal lipid absorption.

HY-P2860

Acetylcholinesterase, Fly head
Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors.

HY-U00267

Thiazinamium chloride	Inducer
Thiazinamium (chloride) possesses potent anticholinergic and antiallergic activity and inhibits TxB2 synthesis with IC₅₀ value of 0.2 µM. Thiazinamium (chloride) is structurally similar to H-1 antagonists Promethazine (HY-B1296). Thiazinamium (chloride) stimulates the phosphatidylcholine secretion in adult rat type II pneumocytes.

HY-173486

BuChE-IN-21	Inhibitor
BuChE-IN-21 (compound SXF3) is a potent and selective BuChE inhibitor. BuChE-IN-21 inhibits eqBuChE and hBuChE with IC₅₀s of 0.05 and 0.04 μM, respectively. BuChE-IN-21 has high anti-inflammatory activity.

HY-W753485

Profenofos-d₃
Profenofos-d₃ is the deuterium labeled Profenofos (HY-B0832). Profenofos is an insecticida used on field crops, vegetables, and fruit crops. Profenofos is an acetylcholinesterase (AChE) inhibitor, with neurotoxicity.

HY-131922

Iso-OMPA	Inhibitor	99.90%
Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE).

HY-B2152

Hemicholinium 3	Inhibitor	99.85%
Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a K_i value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh). Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [³H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively.

HY-136610

Chlorpyrifos-oxon	Inhibitor	99.39%
Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a potent phosphorylating agent that potently inhibits AChE. Chlorpyrifos-oxon can induce cross-linking between subunits of tubulin and disrupt microtubule function.

HY-Y0320D

Dimethyl sulfoxide, cryoprotectant vitrification agent	Inhibitor	99.70%
Dimethyl sulfoxide, cryoprotectant vitrification agent (DMSO, cryoprotectant vitrification agent) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. This product has been sterilized and has no endotoxin. It can be used for long-term cell cryopreservation and will not affect the normal growth of cells.

HY-N0793

Protopine	Inhibitor	99.81%
Protopine (Corydinine), an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity.

HY-B1337S

Choline-d₄ chloride		99.66%
Choline-d₄ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337S1

Choline-d₉ chloride		99.77%
Choline-d₉ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B0423

Neostigmine Bromide	Inhibitor	99.91%
Neostigmine (Eustigmin) Bromide is an orally active and reversible cholinesterase inhibitor that acts on myasthenia gravis to prolong and intensify the muscarinic and nicotinic effects of acetylcholine. Neostigmine Bromide can be used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers.

HY-N6608

Physostigmine	Inhibitor	99.92%
Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning.

HY-B1206

Neostigmine methyl sulfate	Inhibitor	99.50%
Neostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier.

HY-Y0504

Trimethylammonium chloride	Inhibitor	≥98.0%
Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase.

HY-W013175

Uridine 5'-monophosphate disodium salt	Activator	99.90%
Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

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