1. Metabolic Enzyme/Protease Neuronal Signaling
  2. Cholinesterase (ChE) Endogenous Metabolite
  3. Trimethylammonium chloride

Trimethylammonium chloride  (Synonyms: Hegzadesil; Trimethylamine hydrochloric acid; Trimethylamine monohydrochloride)

Cat. No.: HY-Y0504 Purity: ≥98.0%
Handling Instructions Technical Support

Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase.

For research use only. We do not sell to patients.

Trimethylammonium chloride Chemical Structure

Trimethylammonium chloride Chemical Structure

CAS No. : 593-81-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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10 mM * 1 mL in DMSO In-stock
Solid
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Description

Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase[1][2].

Molecular Weight

95.57

Formula

C3H10ClN

CAS No.
Appearance

Solid

Color

Colorless to off-white

SMILES

CN(C)C.[H]Cl

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, stored under nitrogen, away from moisture

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 200 mg/mL (2092.71 mM; Need ultrasonic)

DMSO : 41.67 mg/mL (436.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.4635 mL 52.3177 mL 104.6353 mL
5 mM 2.0927 mL 10.4635 mL 20.9271 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 10.4635 mL 52.3177 mL 104.6353 mL 261.5884 mL
5 mM 2.0927 mL 10.4635 mL 20.9271 mL 52.3177 mL
10 mM 1.0464 mL 5.2318 mL 10.4635 mL 26.1588 mL
15 mM 0.6976 mL 3.4878 mL 6.9757 mL 17.4392 mL
20 mM 0.5232 mL 2.6159 mL 5.2318 mL 13.0794 mL
25 mM 0.4185 mL 2.0927 mL 4.1854 mL 10.4635 mL
30 mM 0.3488 mL 1.7439 mL 3.4878 mL 8.7196 mL
40 mM 0.2616 mL 1.3079 mL 2.6159 mL 6.5397 mL
50 mM 0.2093 mL 1.0464 mL 2.0927 mL 5.2318 mL
60 mM 0.1744 mL 0.8720 mL 1.7439 mL 4.3598 mL
80 mM 0.1308 mL 0.6540 mL 1.3079 mL 3.2699 mL
100 mM 0.1046 mL 0.5232 mL 1.0464 mL 2.6159 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Trimethylammonium chloride
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