2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. 11β-HSD
  5. 11β-HSD Inducer

11β-HSD Inducer

11β-HSD Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-174908
    SJL2-1
    		Inducer
    SJL2-1 is a PRMT5 inhibitor, with an IC50 of 1.56 μM. SJL2-1 suppresses proliferation, migration, and invasion in prostate cancer cells. SJL2-1 promotes apoptosis and blocks the cell cycle at the G0/G1 phase. SJL2-1 can target the binding of PRMT5 in cells and inhibit the methylation and expression of the androgen receptor. SJL2-1 can be used for the study of early androgen-sensitive prostate cancer and advanced castration-resistant prostate cancer (CRPC).