1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W015879S
    2-Heptanol-d5 98%
    2-Heptanol-d5 is deuterated labeled 2-Heptanol (HY-W015879). 2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties.
    2-Heptanol-d5
  • HY-W016221R
    6-Hydroxy Chlorzoxazone (Standard) 1750-45-4
    6-Hydroxy Chlorzoxazone (Standard) is the analytical standard of 6-Hydroxy Chlorzoxazone. This product is intended for research and analytical applications. 6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort.
    6-Hydroxy Chlorzoxazone (Standard)
  • HY-W018025R
    5,6-Dihydroxyindole (Standard) 3131-52-0
    5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens.
    5,6-Dihydroxyindole (Standard)
  • HY-W018800R
    4(3H)-Quinazolinone (Standard) 491-36-1
    4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities.
    4(3H)-Quinazolinone (Standard)
  • HY-W019721R
    Cyclosporin D (Standard) 63775-96-2
    Cyclosporin D (Standard) is the analytical standard of Cyclosporin D. This product is intended for research and analytical applications. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc).
    Cyclosporin D (Standard)
  • HY-W021267R
    3-Demethylcolchicine (Standard) 7336-33-6
    3-Demethylcolchicine (Standard) is the analytical standard of 3-Demethylcolchicine. This product is intended for research and analytical applications. 3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema.
    3-Demethylcolchicine (Standard)
  • HY-W027951R
    N,N'-Dimethylthiourea (Standard) 534-13-4
    N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action.
    N,N'-Dimethylthiourea (Standard)
  • HY-W040265R
    Fenamic acid (Standard) 91-40-7
    Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent-.
    Fenamic acid (Standard)
  • HY-W040672R
    Ibufenac (Standard) 1553-60-2
    Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis.
    Ibufenac (Standard)
  • HY-W050154R
    Kojic acid (Standard) 501-30-4
    Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields.
    Kojic acid (Standard)
  • HY-W067056R
    Methyl (E)-cinnamate (Standard) 1754-62-7
    Methyl (E)-cinnamate (Standard) is the analytical standard of Methyl (E)-cinnamate. This product is intended for research and analytical applications. Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry.
    Methyl (E)-cinnamate (Standard)
  • HY-W086896R
    α-Demethylnaproxen (Standard) 23981-47-7
    α-Demethylnaproxen (Standard) is the analytical standard of α-Demethylnaproxen. This product is intended for research and analytical applications. α-Demethylnaproxen is the major metabolite of Nabumetone (HY-B0559), Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity.
    α-Demethylnaproxen (Standard)
  • HY-W087988R
    3-Pentanol (Standard) 584-02-1
    3-Pentanol (Standard) is an analytical reference standard of 3-Pentanol. 3-Pentanol is an active organic compound produced by plants and is a component of insect-released pheromones. 3-Pentanol can trigger plant immunity against microbial pathogens and pests in crops by activating the SA and JA signaling pathways.
    3-Pentanol (Standard)
  • HY-W094747A
    Benzalazine 588-68-1 98.82%
    Benzalazine is a 5-azo derivative of 5-Aminosalicylic Acid (HY-15027) that can be used for the research of ulcerative colitis and Crohn's disease of the large intestine. The benzalazine metabolite 5-ASA and the 5-ASA metabolite acetyl-5-aminosalicylic acid are excreted mainly with the faeces.
    Benzalazine
  • HY-W099331R
    Monoethylglycinexylidide hydrochloride (Standard) 7729-94-4
    Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
    Monoethylglycinexylidide hydrochloride (Standard)
  • HY-W278867R
    trans-3,5-Dimethoxystilbene (Standard) 21956-56-9
    trans-3,5-Dimethoxystilbene (cis-Pinosylvin dimethyl ether) is a compound that has been isolated from the benzene extract of the bark of jack pine (Pinus bunksiuna).
    trans-3,5-Dimethoxystilbene (Standard)
  • HY-W592871R
    10-Hydroxy-2-decenoic acid (Standard) 765-01-5
    10-Hydroxy-2-decenoic acid (Standard) is an analytical standard for 10-Hydroxy-2-decenoic acid (HY-W592871). This product is intended for research and analytical applications.10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-α signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence.
    10-Hydroxy-2-decenoic acid (Standard)
  • HY-W714076R
    Ametoctradin (Standard) 865318-97-4
    Ametoctradin (Standard) is the analytical standard of Ametoctradin. This product is intended for research and analytical applications. Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews.
    Ametoctradin (Standard)
  • HY-W751034A
    (R)-Ozanimod hydrochloride 1306760-85-9 98%
    (R)-Ozanimod (hydrochloride) is the R-isomer of Ozanimod hydrochloride (HY-12288A).
    (R)-Ozanimod hydrochloride
  • HY-W763569A
    Hydrolyzed Glutenin 8002-80-0 98%
    Hydrolyzed Glutenin is a kind of wheat protein. Glutenin has a unique amino acid chain where glutamic acid, proline, and leucine constitute about 50% of the amino acids.
    Hydrolyzed Glutenin
Cat. No. Product Name / Synonyms Application Reactivity