2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W109401
    SIRT-IN-6 1431411-18-5 98%
    SIRT-IN-6 (Compound 14) is a pan-inhibitor of SIRT1/2/3 with IC50 values of >50 μM. SIRT-IN-6 is promising for research of metabolic, inflammatory, oncologic and neurodegenerative disorders.
    SIRT-IN-6
  • HY-W130878
    4-Octylphenol 1806-26-4 98%
    4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway.
    4-Octylphenol
  • HY-W162983
    3,4-Diphenyl-5H-furan-2-one 5635-16-5 98%
    3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain.
    3,4-Diphenyl-5H-furan-2-one
  • HY-W173309
    Lonazolac 53808-88-1 99.59%
    Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects .
    Lonazolac
  • HY-W176576
    Falimint 553-20-8 99.86%
    Falimint is an antipyretic and analgesic compound.
    Falimint
  • HY-W179151
    N-Octanoyl dopamine 105026-81-1 98%
    N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells.
    N-Octanoyl dopamine
  • HY-W184893
    Atranol 526-37-4
    Atranol is a strong contact allergen found in oak moss absolute (OMA). Atranol causes contact dermatitis by inducing immune system allergic reactions. Atranol is promising for research of etiology of contact dermatitis and cosmetic allergens.
    Atranol
  • HY-W237498
    Urease-IN-17 4322-58-1 98%
    Urease-IN-17 (9) is a urease inhibitor, with an IC50 of 84 μM.
    Urease-IN-17
  • HY-W268942
    4-Nitrosodiphenylamine 156-10-5 98%
    4-Nitrosodiphenylamine shows great antibacterial activity against Erwinia amylovora, with an EC50 value of 5.715 mg/L.
    4-Nitrosodiphenylamine
  • HY-W273493
    4-Nitrochalcone 1222-98-6 98%
    4-Nitrochalcone (2-(4-Nitrobenzylidene)acetophenone) inhibits the proteasome, inhibits NF-κB activity induced by TNFα.
    4-Nitrochalcone
  • HY-W276446
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol 968-63-8 98%
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent. 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol has the potential for the research of bronchial asthma. 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol
  • HY-W285243
    3′-Hydroxyflavanone 92496-65-6 98%
    3′-Hydroxyflavanone is a cyclized flavanone. 3′-Hydroxyflavanone induces apoptosis in HeLa cells. 3′-Hydroxyflavanone possesses antitumor activity.
    3′-Hydroxyflavanone
  • HY-W286614
    RSK2-IN-4 62001-32-5 98%
    RSK2-IN-4 (Compound 10) is a RSK2 inhibitor, with an inhibition rate of 13.73% on RSK2 activity at 10 μM. RSK2-IN-4 binds to the ATP-binding site of RSK2 in the NTKD (N-terminal kinase domain), with the electron-donating group at the 4-position of the phenyl ring being the key determinant for its inhibitory activity .
    RSK2-IN-4
  • HY-W288025
    ALXR-agonist-6 325850-26-8 98%
    ALXR-agonist-6 (compound 36) is an ALXR agonist with the EC50 values of >10 μM for Ca2+ flux in CHO recombinant cells co-expressing hFPRL1.
    ALXR-agonist-6
  • HY-W335896
    4-(2-Octylamino)diphenylamine 15233-47-3 98%
    4-(2-Octylamino)diphenylamine is an aromatic amine antioxidant, which is toxic to V. fischeri with an IC50 value of 0.68 mg/mL. 4-(2-Octylamino)diphenylamine induces skin sensitization and contact dermatitis in a local lymph node assay in mice. 4-(2-Octylamino)diphenylamine can be used as an additive in rubber.
    4-(2-Octylamino)diphenylamine
  • HY-W345359
    PAF C-18:1 85966-90-1 98%
    PAF C-18:1 is a naturally occurring phospholipid produced by cells upon inflammatory responses. PAF C-18:1 is a chemoattractant, and induces human neutrophil chemotaxis.
    PAF C-18:1
  • HY-W354369
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid 50264-63-6 98%
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid is a MRGPRX4 antagonist (IC50: >2.5 μM).
    1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
  • HY-W357141
    Methyl 2-O-β-D-glucopyranosylbenzoate 10019-60-0
    Methyl 2-O-β-D-glucopyranosylbenzoate (Methyl salicylate 2-O-β-D-glucopyranoside) (Compound 11) is a phenolic compound. Methyl 2-O-β-D-glucopyranosylbenzoate can be isolated from the leaves of Metapanax delavayi. Methyl 2-O-β-D-glucopyranosylbenzoate has anti-benign prostatic hyperplasia activities and significantly inhibits the proliferation of BPH-1 cells. β-Phenylethyl β-D-glucoside can be used for prostatitis research.
    Methyl 2-O-β-D-glucopyranosylbenzoate
  • HY-W396889
    (R)-N-(1-Hydroxypropan-2-yl)palmitamide 142128-47-0 98%
    (R)-N-(1-Hydroxypropan-2-yl)palmitamide (compound 24) is a substrate analog inhibitor of phospholipase A2.
    (R)-N-(1-Hydroxypropan-2-yl)palmitamide
  • HY-W408607
    N-Benzylacetamidine hydrobromide 186545-76-6 98%
    N-Benzylacetamidine (hydrobromide) is a acetamidine compound. N-Benzylacetamidine (hydrobromide) is a selective inducible nitric oxide synthase (iNOS) inhibitor with an IC50 of 0.20 μM.
    N-Benzylacetamidine hydrobromide
Cat. No. Product Name / Synonyms Application Reactivity