2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-17507AR
    Pantoprazole sodium (Standard) 138786-67-1
    Pantoprazole (sodium) (Standard) is the analytical standard of Pantoprazole (sodium). This product is intended for research and analytical applications. Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole sodium, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole sodium (Standard)
  • HY-17507BR
    Pantoprazole sodium hydrate (Standard) 164579-32-2
    Pantoprazole (sodium hydrate) (Standard) is the analytical standard of Pantoprazole (sodium hydrate). This product is intended for research and analytical applications. Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole sodium hydrate (Standard)
  • HY-17507S1
    Pantoprazole-d3 922727-37-5 98%
    Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole-d3
  • HY-175310S
    Voderdeucitinib 2824164-00-1 98%
    Voderdeucitinib (Compoudn I) is a TYK2 inhibitor with an anti-inflammatory activity. Voderdeucitinib can be used for inflammatory and autoimmune disease research, such as rheumatoid arthritis (RA), multiple sclerosis and intestinal bowel disease (IBD).
    Voderdeucitinib
  • HY-17589S1
    Chloroquine-d4 phosphate 98%
    Chloroquine-d4 (phosphate) is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
    Chloroquine-d4 phosphate
  • HY-176277S
    Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,15N4) TFA
    Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,154) TFA is the 13C- and 15N-labeled Fibrinopeptide B, human (HY-P1493). Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
    Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,15N4) TFA
  • HY-177130S
    Socrodeucitinib 2457365-35-2 98%
    Socrodeucitinib (Compound Example 58) is an orally active and selective tyrosine kinase 2 (TYK2) inhibitor with an IC50 value of 1.41 nM. Socrodeucitinib exerts anti-inflammatory activity by inhibiting TYK2-mediated cytokine signaling pathways and reducing the secretion of inflammatory factors. Socrodeucitinib is promising for research of autoimmune diseases such as psoriasis and inflammatory diseases.
    Socrodeucitinib
  • HY-177611A
    Agazisiran sodium 98%
    Agazisiran sodium, a siRNA,is a complement factor B synthesis reducer.
    Agazisiran sodium
  • HY-177621A
    Cevolisiran sodium 98%
    Cevolisiran sodium, a siRNA, is a complement component 3 (C3) synthesis reducer.
    Cevolisiran sodium
  • HY-177623A
    CpG-ODN c41 sodium
    CpG-ODN c41 sodium, an oligonucleotide, is an antagonist of TLR9.
    CpG-ODN c41 sodium
  • HY-177624A
    Cupabimod sodium
    Cupabimod sodium is a decoy oligodeoxynucleotide for transcription factor NF-κB.
    Cupabimod sodium
  • HY-177627A
    Edifoligide sodium
    Edifoligide sodium is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure
    Edifoligide sodium
  • HY-177652A
    Onvuzosiran sodium 98%
    Onvuzosiran sodium, a siRNA, is a prekallikrein synthesis reducer.
    Onvuzosiran sodium
  • HY-178762S
    RIPK1-IN-35 98%
    RIPK1-IN-35 is a selective and orally active RIPK1 inhibitor with an IC50 of 5.33 nM. RIPK1-IN-35 has a potent protective effect against necroptosis in both human and murine cells. RIPK1-IN-35 shows good therapeutic effects in both TNF-α-induced systemic inflammatory response syndrome and DSS (HY-116282C)-induced inflammatory bowel disease models. RIPK1-IN-35 can be used to the study of inflammatory diseases related to necroptosis.
    RIPK1-IN-35
  • HY-18234AR
    Leupeptin hemisulfate (Standard) 103476-89-7
    Leupeptin (hemisulfate) (Standard) is the analytical standard of Leupeptin (hemisulfate). This product is intended for research and analytical applications. Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits Mpro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity[1][2][3].
    Leupeptin hemisulfate (Standard)
  • HY-30235AR
    Benzydamine hydrochloride (Standard) 132-69-4 98%
    Benzydamine (hydrochloride) (Standard) is the analytical standard of Benzydamine (hydrochloride). This product is intended for research and analytical applications. Benzydamine hydrochloride is a prostaglandin synthase inhibitor, anti-inflammatory, and has also been reported to have antibacterial activity.
    Benzydamine hydrochloride (Standard)
  • HY-400540A
    Padoprazanum fumarate 2938973-98-7
    Padoprazanum (Padoprazan) fumarate is a Proton Pump inhibitor.
    Padoprazanum fumarate
  • HY-42682S1
    D(+)-Galactosamine-13C hydrochloride 478518-54-6 99.0%
    D(+)-Galactosamine-13C (hydrochloride) is the 13C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and
    D(+)-Galactosamine-13C hydrochloride
  • HY-66005S3
    Acetaminophen-13C6 2132405-57-1 98%
    Acetaminophen-13C6 (Paracetamol-13C6) is the 13C-labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-13C6
  • HY-66008S1
    N-Acetyl mesalazine-d3-1 1309935-89-4 98%
    N-Acetyl mesalazine-d3-1 (N-Acetyl-5-aminosalicylic acid-d3-1) is deuterium labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer.
    N-Acetyl mesalazine-d3-1
Cat. No. Product Name / Synonyms Application Reactivity