1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1471R
    Liquiritin apioside (Standard) 74639-14-8
    Liquiritin apioside (Standard) is the analytical standard of Liquiritin apioside. This product is intended for research and analytical applications. Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects.
    Liquiritin apioside (Standard)
  • HY-N1474R
    Picfeltarraenin IA (Standard) 97230-47-2
    Picfeltarraenin IA (Standard) is the analytical standard of Picfeltarraenin IA. This product is intended for research and analytical applications. Picfeltarraenin IA, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IA can be used for the treatment of herpes infections, cancer and inflammation.
    Picfeltarraenin IA (Standard)
  • HY-N14765
    7-Demethylnaphterpin 137109-43-4 98%
    7-Demethylnaphterpin (Naphthgeranine A) is a free radical scavenger that can be isolated from Streptomyces prunicolor.
    7-Demethylnaphterpin
  • HY-N1485R
    Cycloastragenol (Standard) 78574-94-4 98%
    Cycloastragenol (Standard) is the analytical standard of Cycloastragenol. This product is intended for research and analytical applications. Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties.
    Cycloastragenol (Standard)
  • HY-N1486R
    Ursonic acid (Standard) 6246-46-4
    CSRM617 (Standard) is the analytical standard of CSRM617. This product is intended for research and analytical applications. CSRM617 is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 is well tolerated in the prostate cancer mouse model
    Ursonic acid (Standard)
  • HY-N1490R
    14-Deoxy-11,12-didehydroandrographolide (Standard) 42895-58-9
    14-Deoxy-11,12-didehydroandrographolide (Standard) is the analytical standard of 14-Deoxy-11,12-didehydroandrographolide. This product is intended for research and analytical applications. 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.
    14-Deoxy-11,12-didehydroandrographolide (Standard)
  • HY-N1495R
    Maltopentaose (Standard) 34620-76-3
    Maltopentaose (Standard) is the analytical standard of Maltopentaose. This product is intended for research and analytical applications. Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin.
    Maltopentaose (Standard)
  • HY-N1499R
    Nystose (Standard) 13133-07-8 98%
    Nystose (Standard) is the analytical standard of Nystose. This product is intended for research and analytical applications. Nystose is a tetrasaccharide with two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose. Nystose exhibits prebiotic, immunomodulatory, and metabolism regulating activities. Nystose promotes the bone mineralization by activating the Wnt/β-catenin signaling pathway.
    Nystose (Standard)
  • HY-N15177
    Δ9-THCB 60008-00-6 98%
    Δ9-THCB (Δ9-Tetrahydrocannabutol) has a high affinity for human CB1 and CB2 receptors with the Ki values of 15 nM and 51 nM, respectively. Δ9-THCB (Δ9-Tetrahydrocannabutol) has analgesic and anti-inflammatory activities and plays partial agonistic effects on CB1 receptor in mice.
    Δ9-THCB
  • HY-N1517R
    Ganoderic acid C2 (Standard) 103773-62-2
    Ganoderic acid C2 (Standard) is the analytical standard of Ganoderic acid C2. This product is intended for research and analytical applications. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM.
    Ganoderic acid C2 (Standard)
  • HY-N15219
    6-Hydroxygenistein-7-O-β-D-glucopyranoside 198135-88-5 98%
    6-Hydroxygenistein-7-O-β-D-glucopyranoside (compound 2) is a glucopyranoside that can be isolated from Pueraria lobata flower. The isoflavones in Pueraria lobata flower are potential anti-inflammatory agents for microglia and can inhibit the production of NO.
    6-Hydroxygenistein-7-O-β-D-glucopyranoside
  • HY-N15221
    12-Acetoxyganoderic acid D 2374206-92-3 98%
    12-Acetoxyganoderic acid D is a triterpenoid compound found in Ganoderma sinense. 12-Acetoxyganoderic acid D exhibits certain anti-inflammatory activity and inhibits NO production in LPS (HY-D1056) stimulated RAW 264.7 macrophages.
    12-Acetoxyganoderic acid D
  • HY-N15226
    Butyrolactone Ia 942986-92-7 98%
    Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS (HY-D1056)-induced mRNA expression of iNOS and the inflammatory cytokine IL-1β. Butyrolactone Ia modulates autophagy in HeLa cells, and exhibits immune suppressive activity.
    Butyrolactone Ia
  • HY-N15230
    Torososide B 243835-63-4 98%
    Torososide B is an antiallergic compound that inhibits calcium ionophore A-induced leukotriene release from rat peritoneal mast cells.
    Torososide B
  • HY-N15305
    Ferolin 39380-12-6 98%
    Ferolin is the agonist for farnesoid X receptor (FXR) with an EC50 of 0.56 µM. Ferolin inhibits the expression of inflammatory genes (such as iNOS, IL-1β and TNFα) upon the FXR activation.
    Ferolin
  • HY-N15447
    Visnaginone 484-27-5 98%
    Visnaginone is the derivative of Visnagin (HY-N1082). Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles.
    Visnaginone
  • HY-N15452
    Eseramine 6091-57-2 98%
    Eseramine is a weak acetylcholinesterase inhibitor with an IC50 value of 9300 nM. Eseramine is promising for research of diseases involving the regulation of acetylcholinesterase, such as glaucoma, myasthenia gravis, and protection against organophosphate poisoning.
    Eseramine
  • HY-N15501
    Trichaspside F 3075431-03-4 98%
    Trichaspside F is a sesquiterpene aminoglycoside compound discovered from Trichoderma sp. SCSIOW21. Trichaspside F has the activity of inhibiting the production of NO. In the experiment with macrophage RAW 264.7 cells, its IC50 value for inhibiting the production of NO is 54.8 µM. Trichaspside F can be used in the research of the anti-inflammatory field.
    Trichaspside F
  • HY-N15502
    Cycloneroside A 3075431-04-5 98%
    Cycloneroside A is a sesquiterpene aminoglycoside compound discovered from Trichoderma sp. SCSIOW21. Cycloneroside A has the activity of inhibiting the production of NO. In the experiment with macrophage RAW 264.7 cells, its IC50 value for inhibiting the production of NO is approximately 100 µM. Cycloneroside A can be used in the research of the anti-inflammatory field.
    Cycloneroside A
  • HY-N15503
    Cycloneroside B 3075431-05-6 98%
    Cycloneroside B is a novel sesquiterpene aminoglycoside compound that can be isolated from Trichoderma sp. SCSIOW21. Cycloneroside B has the activity of inhibiting the production of NO, and its IC50 value for inhibiting the production of NO is 50.7 µM. Cycloneroside B can be used in the research of the anti-inflammatory field.
    Cycloneroside B
Cat. No. Product Name / Synonyms Application Reactivity