2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-161381
    PDE4-IN-15 3034837-89-0 98%
    PDE4-IN-15 (compound 7b-1) is an inhibitor of PDE4 (IC50 = 0.17 μM) and has anti-TNF-α activity (EC50 = 0.19 μM). PDE4-IN-15 has a good skin permeability.
    PDE4-IN-15
  • HY-161389
    SP-alkyne 98%
    SP-alkyne (compound 8) suppresses IL-2 production and AP-1 and NFAT reporters.
    SP-alkyne
  • HY-161390
    SPC-alkyne 98%
    SPC-alkyne (compound 9) is an alkynyl derivative. SPC-alkyne suppresses IL-2 production and AP-1 and NFAT reporters.
    SPC-alkyne
  • HY-161396
    Anti-inflammatory agent 76 98%
    Anti-inflammatory agent 76 (Compd 8b), an anti-inflammatory agent, exhibits good NO, IL-1β and IL-6 inhibitory activities.
    Anti-inflammatory agent 76
  • HY-161397
    NA-1-157 98%
    NA-1-157 is a potent irreversible covalent inhibitor of the GES-5 carbapenemase, with a MIC of 0.5 μg/mL.
    NA-1-157
  • HY-161413
    Antibacterial agent 204 1211465-32-5 98%
    Antibacterial agent 204 (Compd P2-56-3) possesses potentiated Rifampin (RIF) activity against Acinetobacter baumannii and Klebsiella pneumoniae. Antibacterial agent 204 (Compd P2-56-3) disrupts the outer membrane of A. baumannii. T.
    Antibacterial agent 204
  • HY-161441
    SIK-IN-2 3033846-20-4 98%
    SIK-IN-2 (Compound 45) is an inhibitor for salt-inducible kinase (SIK), which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.2 and 0.4 nM, respectively. SIK-IN-2 inhibits the release of TNFa with IC50 of 0.5 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC50 of 2 nM in human macrophages.
    SIK-IN-2
  • HY-161442
    SIK-IN-3 98%
    SIK-IN-3 (Compound 6B) is an inhibitor for salt-inducible kinase (SIK), which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.3 and 0.8 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC50 of 0.6 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC50 of 3 nM in human macrophages.
    SIK-IN-3
  • HY-161455
    Xanthine oxidase-IN-13 98%
    Xanthine oxidase-IN-13 (Compound 10) is a selective xanthine oxidase inhibitor (IC50: 149.56 μM for bovine xanthine oxidase). Xanthine oxidase-IN-13 can be used for research of inflammatory arthritis.
    Xanthine oxidase-IN-13
  • HY-161465
    HDAC8-IN-7 98%
    HDAC8-IN-7 (H7E), a HDAC8 inhibitor, exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress. HDAC8-IN-7 alleviates functional and structural defects within the inner retina.
    HDAC8-IN-7
  • HY-161471
    DCLK1-IN-5 3028774-14-0 98%
    DCLK1-IN-5 (Compound a24) is a DCLK1 inhibitor (IC50: 179.7 nM). DCLK1-IN-5 inhibits lipopolysaccharide (HY-D1056)-induced inflammation via inhibiting DCLK1-mediated IKKβ phosphorylation. DCLK1-IN-5 protects mice against inflammation-induced lung injury and sepsis.
    DCLK1-IN-5
  • HY-161477
    Histamine/BSA 98%
    Histamine/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Histamine/BSA
  • HY-161478
    Phosphoserine/BSA 98%
    Phosphoserine/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Phosphoserine/BSA
  • HY-161479
    Melamine/OVA 98%
    Melamine/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Melamine/OVA
  • HY-161480
    Melamine/BSA 98%
    Melamine/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Melamine/BSA
  • HY-161481
    Melamine/bov igG 98%
    Melamine/bov igG is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Melamine/bov igG
  • HY-161482
    Alginic acid/BSA 98%
    Alginic acid/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Alginic acid/BSA
  • HY-161484
    Penicillin G/OVA 98%
    Penicillin G/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Penicillin G/OVA
  • HY-161485
    Gentamicin/BSA 98%
    Gentamicin/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Gentamicin/BSA
  • HY-161486
    AOZ/OVA 98%
    AOZ/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    AOZ/OVA
Cat. No. Product Name / Synonyms Application Reactivity