2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-120794
    SC-67655 182134-00-5 98%
    SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC50 of 50 nM. SC 67655 can be used for the study of autoimmune diseases.
    SC-67655
  • HY-120802
    Navafenterol 1435519-06-4 98%
    Navafenterol (AZD-8871) is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile.
    Navafenterol
  • HY-120804
    PH-46A 1380445-04-4 98%
    PH-46A is an indane dimer with anti-inflammatory activity. PH-46A can reduced histological damage and serum amyloid A (SAA) levels in colitis mice.
    PH-46A
  • HY-120829
    Bisoprolol fumarate 105878-43-1 98%
    Bisoprolol fumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol fumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research.
    Bisoprolol fumarate
  • HY-120845
    Tr-PEG5-OH 141282-24-8
    Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    Tr-PEG5-OH
  • HY-120867
    TASP0376377 1233246-60-0 98%
    TASP0376377 is a potent and selective CRTH2 antagonist (IC50: 13 nM). TASP0376377 has binding affinity for CRTH2 (IC50: 19 nM).
    TASP0376377
  • HY-120876
    L-680833 127063-08-5 98%
    L-680833 is a monocyclic β-lactam inhibitor of human polymorphonuclear leukocyte elastase (PMNE) inhibitor. L-680833 can be used for the study of PMNE-damaged tissue diseases.
    L-680833
  • HY-120928
    S 16474 149250-10-2 98%
    S 16474 is a cyclic peptide with antagonistic effects on NK1 and NK2 receptors. S 16474 can be used in the study of neurogenic inflammation.
    S 16474
  • HY-120941
    LASSBio-1359 1396397-19-5 98%
    LASSBio-1359 is an adenosine A2A receptor agonist with vasodilatory and anti-inflammatory activities.
    LASSBio-1359
  • HY-120944
    BAY-7598 1816257-74-5 98%
    BAY-7598, a chemical probe, is a potent, orally bioavailable, and selective MMP12 inhibitor with IC50s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively.
    BAY-7598
  • HY-120953
    GAT228 1446648-15-2 98%
    GAT228, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand.
    GAT228
  • HY-120966
    NCX 2121 301838-28-8 98%
    NCX 2121 (NO-indomethacin) is an anti-inflammatory agent. NCX 2121 inhibits PaCa-2 cells growth witn an IC50 of 82 μM.
    NCX 2121
  • HY-120975
    2,3-Dinor thromboxane b1 196493-76-2 98%
    2,3-Dinor thromboxane b1 is an urinary metabolite of Thromboxane B2 (HY-113331).
    2,3-Dinor thromboxane b1
  • HY-12100S
    Umeclidinium-d5 bromide 98%
    Umeclidinium-d5 (bromide) is the deuterium labeled Umeclidinium bromide. Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.
    Umeclidinium-d5 bromide
  • HY-121038
    Chamazulene 529-05-5 98%
    Chamazulene, a natural compound, is an antioxidant-type inhibitor of leukotriene B4 formation.
    Chamazulene
  • HY-121043
    AA 497 free base 59605-49-1 98%
    AA 497 free base is an adrenergic beta-2 agonist. AA 497 free base is a bronchodilator.
    AA 497 free base
  • HY-121046
    Flunixin 38677-85-9 98%
    Flunixin is a cyclooxygenase (COX) inhibitor with IC50 values of 0.55 and 3.24 μM for COX-1 and COX-2, respectively. Flunixin shows anti-inflammatory effects.
    Flunixin
  • HY-121062
    Betamethasone acibutate 5534-05-4 98%
    Betamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid.
    Betamethasone acibutate
  • HY-121076
    Berteroin 4430-42-6 98%
    Berteroin, a naturally occurring Sulforaphane analog, ia an antimetastatic agent. Berteroin has anti-inflammatory, antitumor and bactericidal effects.
    Berteroin
  • HY-121097
    Diapocynin 29799-22-2 99.0%
    Diapocynin (Dehydrodiacetovanillone), a dimeric derivative of Apocynin, is an orally active NADPH oxidase inhibitor. Diapocynin has anti-inflammatory, neuroprotection and antioxidant activities.
    Diapocynin
Cat. No. Product Name / Synonyms Application Reactivity