2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1065
    Apelin-36(rat, mouse) 230299-95-3 99.12%
    Apelin-36(rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
    Apelin-36(rat, mouse)
  • HY-P1116
    PBP10 794466-43-6 98.13%
    PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects.
    PBP10
  • HY-P1350
    H-Lys-Trp-Lys-OH 38579-27-0 99.97%
    H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.
    H-Lys-Trp-Lys-OH
  • HY-P2317
    Cecropin P1, porcine 125667-96-1 99.83%
    Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection.
    Cecropin P1, porcine
  • HY-P4648
    H-Trp-Trp-Trp-OH 59005-82-2 99.87%
    H-Trp-Trp-Trp-OH is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity.
    H-Trp-Trp-Trp-OH
  • HY-100589
    Isepamicin sulfate 67814-76-0 ≥98.0%
    Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance.
    Isepamicin sulfate
  • HY-101011
    Naloxonazine dihydrochloride 880759-65-9 ≥98.0%
    Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5.4 nM. Naloxonazine dihydrochloride also shows anti-leishmanial activity.
    Naloxonazine dihydrochloride
  • HY-106755
    Tucaresol 84290-27-7 98.95%
    Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect.
    Tucaresol
  • HY-107814
    Nicarbazin 330-95-0 ≥98.0%
    Nicarbazin is an effective anticoccidial agent for chickens.
    Nicarbazin
  • HY-108700
    N-3-Oxo-octanoyl-L-homoserine lactone 147795-39-9 98.05%
    N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer.
    N-3-Oxo-octanoyl-L-homoserine lactone
  • HY-108941
    Salicyl-AMS 863238-55-5 99.59%
    Salicyl-AMS is a mycobactin biosynthesis inhibitor which can also inhibit M. tuberculosis growth in vitro under iron-limited conditions.
    Salicyl-AMS
  • HY-108970
    Bafilomycin D 98813-13-9 99.30%
    Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity.
    Bafilomycin D
  • HY-109195
    Vebicorvir 2090064-66-5 99.73%
    Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM.
    Vebicorvir
  • HY-111009
    Swinholide A 95927-67-6 98.30%
    Swinholide A is the actin-binding marine polyketide and dimerizes actin with the Kd of ~ 50 nM. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. Swinholide A disrupts the actin cytoskeleton of cells.Antifungal activity.
    Swinholide A
  • HY-111086
    DG70 930470-97-6 99.91%
    DG70 (GSK1733953A), a biphenyl amide, is a respiration inhibitor in Mycobacterium tuberculosis, inhibits MenG activity with an IC50 value of 2.6 ± 0.6 μM. DG70 inhibits the catalytic methylation of Mycobacterium tuberculosis demethylmenaquinone methyltransferase enzymes. DG70 can be used for Tuberculosis (TB) research.
    DG70
  • HY-112542
    Nemadectin 102130-84-7 99.79%
    Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
    Nemadectin
  • HY-113041
    Prostaglandin A2 13345-50-1 ≥99.0%
    Prostaglandin A2 (PGA2), a human endogenous metabolite of PGE2, is an antitumor agent. Prostaglandin A2 induces p53-dependent apoptosis. Prostaglandin A2 also has antiviral activity.
    Prostaglandin A2
  • HY-116214
    Cyprodinil 121552-61-2 99.25%
    Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.
    Cyprodinil
  • HY-116474
    Viridicatol 14484-44-7 99.93%
    Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL.
    Viridicatol
  • HY-116587
    Halocarban 369-77-7 99.82%
    Halocarban is a chemical with antibacterial properties sometimes used in deodorant and soap.
    Halocarban
Cat. No. Product Name / Synonyms Application Reactivity