2. Endocrinology

Endocrinology

Endocrinology

Related Products

PDF 21.44 MB

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1019
    [Ala1,3,11,15]-Endothelin (53-63) 121204-87-3 98%
    [Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction
    [Ala1,3,11,15]-Endothelin (53-63)
  • HY-P1210
    Lys-γ3-MSH(human) 156159-18-1 98%
    Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis.
    Lys-γ3-MSH(human)
  • HY-P1254
    Beta-Lipotropin (1-10), porcine 77875-68-4 98%
    Beta-Lipotropin (1-10), porcine is a porcine-derived fragment of β-lipotropin (1-10), which is a porcine.
    Beta-Lipotropin (1-10), porcine
  • HY-P1276
    Men 10376 135306-85-3 98%
    Men 10376 is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor.
    Men 10376
  • HY-P1298
    Sauvagine 74434-59-6 98%
    Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands.
    Sauvagine
  • HY-P1339
    Orexin B, human 205640-91-1 98%
    Orexin B, human is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
    Orexin B, human
  • HY-P1345
    TLQP-21 869988-94-3 98%
    TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions.
    TLQP-21
  • HY-P1375
    [D-Trp7,9,10]-Substance P 89430-38-6 98%
    [D-Trp7,9,10]-Substance P is a substance P analogue. Substance P stimulates substance P receptors but also inhibits ion conductance through nicotinic acetylcholine receptors.
    [D-Trp7,9,10]-Substance P
  • HY-P1376
    G-Protein antagonist peptide 143675-79-0 98%
    G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. G-Protein antagonist peptide competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.
    G-Protein antagonist peptide
  • HY-P1414
    Canine KP-10 98%
    Canine KP-10 is a potent kisspeptin that elicits strong gonadotropin and estradiol responses in female dogs in estrus.
    Canine KP-10
  • HY-P1418
    DPC-AJ1951 943519-33-3 98%
    DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption.
    DPC-AJ1951
  • HY-P1497
    Bradykinin (1-3) 23815-91-0 98%
    Bradykinin (1-3) is a 3-amino acid residue peptide. Bradykinin (1-3) is an amino-truncated Bradykinin peptide, cleaved by Prolyl endopeptidase.
    Bradykinin (1-3)
  • HY-P1506
    [Nle11]-Substance P 57462-42-7 98%
    [Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.
    [Nle11]-Substance P
  • HY-P1515
    Angiotensin II (3-8), human 12676-15-2 98%
    Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
    Angiotensin II (3-8), human
  • HY-P1532
    Pancreatic Polypeptide, rat 90419-12-8 98%
    Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4.
    Pancreatic Polypeptide, rat
  • HY-P1533
    CRF, bovine 92307-52-3 98%
    CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
    CRF, bovine
  • HY-P1537
    Pancreatic Polypeptide, bovine 179986-89-1 98%
    Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
    Pancreatic Polypeptide, bovine
  • HY-P1545
    ACTH (1-17) 7266-47-9 98%
    ACTH (1-17), an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a Ki of 0.21 nM.
    ACTH (1-17)
  • HY-P1564
    [Sar1, Ile8]-Angiotensin II 37827-06-8 98%
    [Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
    [Sar1, Ile8]-Angiotensin II
  • HY-P1588
    Scyliorhinin II 112748-19-3 98%
    Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.
    Scyliorhinin II
Cat. No. Product Name / Synonyms Application Reactivity