2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-108353
    Isoprenaline 7683-59-2 98%
    Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma.
    Isoprenaline
  • HY-111478
    Tiaprost 71116-82-0 ≥98.0%
    Tiaprost is a prostaglandin F2α (PGF2α) analogue.
    Tiaprost
  • HY-113053
    Prostaglandin A1 14152-28-4 98%
    Prostaglandin A1 is a dehydration derivate of Prostaglandin E1. Prostaglandin A1 exhibits inhibitory activities against tumor growth, inflammation, virus replication, platelet aggregation and excitotoxin-induced neurons apoptosis.
    Prostaglandin A1
  • HY-113351
    11β-Hydroxyandrosterone 57-61-4 ≥99.0%
    11β-Hydroxyandrosterone is a 11-oxygenated androgen metabolite of 11β-hydroxyandrostenedione.
    11β-Hydroxyandrosterone
  • HY-114025
    H4 Receptor antagonist 1 848217-00-5 99.66%
    H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
    H4 Receptor antagonist 1
  • HY-114161
    H-Val-Pro-Pro-OH 58872-39-2 99.86%
    H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM.
    H-Val-Pro-Pro-OH
  • HY-114810
    Prostaglandin F2α serinol amide 1135226-99-1 98%
    Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord.
    Prostaglandin F2α serinol amide
  • HY-118282
    mPGES1-IN-7 1268709-57-4 99.78%
    mPGES-1-IN-2 (compound III) is a benzimidazole-based mPGES-1 inhibitor that also inhibits adipophysin PGD synthase (I-PGDS) (5 μM, IR=60 %). mPGES-1-IN-2 reduces PGE2 production and tends to reduce levels of other prostaglandins. mPGES-1-IN-2 effectively inhibits acute inflammation in an air sac model stimulated by Carrageenan (HY-125474) in mice.
    mPGES1-IN-7
  • HY-118388
    AS604872 612532-48-6 98%
    AS604872 is an orally active, potent and selective prostaglandin F2α receptor (FP) antagonist with a Ki of 35 nM in humans, 158 nM in rats and 323 nM in mice. AS604872 inhibits contractions and delays labour.
    AS604872
  • HY-121580
    Tabimorelin 193079-69-5 98.11%
    Tabimorelin (NN703) is an orally active growth hormone (GH) secretagogue. Tabimorelin is also a potent inhibitor of CYP3A4 activity.
    Tabimorelin
  • HY-12707S
    Piribedil-d8 1398044-45-5 99.79%
    Piribedil-d8 is the deuterium labeled Piribedil, which is an antiparkinsonian agent.
    Piribedil-d8
  • HY-12715S
    Yohimbine-13C,d3 1261254-59-4 ≥99.0%
    Yohimbine-13C,d3 is the 13C- and deuterium labeled Yohimbine. Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
    Yohimbine-13C,d3
  • HY-12718A
    (±)-WB 4101 hydrochloride 2170-58-3
    (±)-WB 4101 is a potent antagonist of noradrenaline. (±)-WB 4101 interacts with protein in smooth muscle. (±)-WB 4101 makes drug and receptor bind tightly.
    (±)-WB 4101 hydrochloride
  • HY-128428
    Carboprost 35700-23-3 ≥98.0%
    Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester.
    Carboprost
  • HY-12987S
    Pimozide-d4 1803193-57-8 ≥98.0%
    Pimozide-d4 is a deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
    Pimozide-d4
  • HY-130660
    Prostaglandin F2α ethanolamide 353787-70-9 98%
    Prostaglandin F2α ethanolamide (Prostamide F2α) is an ethanolamide-like G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord.
    Prostaglandin F2α ethanolamide
  • HY-131256
    Cetirizine Impurity C 83881-59-8 98%
    Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].
    Cetirizine Impurity C
  • HY-134577
    Clorprenaline 3811-25-4 99.33%
    Clorprenaline is a potent agonist of β2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation. Clorprenaline is a potential new lean meat-boosting feed additive.
    Clorprenaline
  • HY-135324
    4,4'-Iminodiphenol 1752-24-5 ≥98.0%
    4-Propionamidophenol (compound 4a) is an inactive estrogen receptor ligand based on the diphenylamine skeleton.
    4,4'-Iminodiphenol
  • HY-13534A
    Abarelix Acetate 547741-72-0 99.89%
    Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.
    Abarelix Acetate
Cat. No. Product Name / Synonyms Application Reactivity