1. Endocrinology

Endocrinology

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-U00168
    KP136 76239-32-2 98%
    KP136 (AL136) is an orally effective antiallergic agent. The IC50 is 76.1 μg/mL for histamine release and 63 ug/mL for degranulation.
    KP136
  • HY-U00170
    Bunaprolast 99107-52-5 98%
    Bunaprolast (U66858) is a potent inhibitor of LTB4 production in human whole blood. Bunaprolast (U66858) also exhibits significant inhibition of lipoxygenase and TXB2 release.
    Bunaprolast
  • HY-U00183
    Epanolol 86880-51-5 98%
    Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
    Epanolol
  • HY-U00188
    A81988 141887-34-5 98%
    A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors.
    A81988
  • HY-U00202
    LY285434 159748-08-0 98%
    LY285434 is a suitable angiotensin II receptor antagonist.
    LY285434
  • HY-U00206
    D2343 72734-63-5 98%
    D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
    D2343
  • HY-U00231
    KF 13218 127654-03-9 98%
    KF 13218 is a potent, selective and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
    KF 13218
  • HY-U00238
    FRG8701 108498-50-6 98%
    FRG-8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.
    FRG8701
  • HY-U00244
    Benzquinamide 63-12-7 98%
    Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively.
    Benzquinamide
  • HY-U00245
    L162441 154512-46-6 98%
    L162441 is an Angiotensin type 1 receptor antagonist.
    L162441
  • HY-U00283
    Falintolol, (Z)- 106401-52-9 98%
    Falintolol, (Z)-, a new β-adrenergic antagonist, is characterized by the presence of an oxime function.
    Falintolol, (Z)-
  • HY-U00289
    Opigolix 912587-25-8 98%
    Opigolix (ASP-1707) is a Gonadotropin-releasing hormone (GnRH) receptor antagonist, used for the research of endometriosis and rheumatoid arthritis.
    Opigolix
  • HY-U00293
    ZK-90055 hydrochloride 84638-81-3 98%
    ZK-90055 hydrochloride is a β2 adrenergic receptor agonist.
    ZK-90055 hydrochloride
  • HY-U00313
    Tropodifene 15790-02-0 98%
    Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.
    Tropodifene
  • HY-U00320
    Neurokinin antagonist 1 214487-45-3 98%
    Neurokinin antagonist 1 is a Neurokinin antagonist extracted from patent WO1998045262A1.
    Neurokinin antagonist 1
  • HY-U00323
    Carbazole derivative 1 164914-28-7 98%
    Carbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.
    Carbazole derivative 1
  • HY-U00333
    α1 adrenoceptor-MO-1 161905-64-2 98%
    α1 adrenoceptor-MO-1, an S enantiomer, has affinity at alpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.
    α1 adrenoceptor-MO-1
  • HY-U00335
    FR252384 447405-11-0 98%
    FR252384 is a neuropeptide Y-Y5 receptor antagonist, with an IC50 of 2.3 nM.
    FR252384
  • HY-U00339
    H3 receptor-MO-1 1240914-03-7 98%
    H3 receptor-MO-1 is a modulator of histamine H3 receptor.
    H3 receptor-MO-1
  • HY-U00353
    MCHR1 antagonist 1 391610-37-0 98%
    MCHR1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
    MCHR1 antagonist 1
Cat. No. Product Name / Synonyms Application Reactivity