2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-D0020R
    2,2'-Bipyridine (Standard) 366-18-7 98%
    2,2'-Bipyridine (Standard) is the analytical standard of 2,2'-Bipyridine. This product is intended for research and analytical applications. 2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center. 2,2'-Bipyridine shows robust redox stability and hyperglycemic activity.
    2,2'-Bipyridine (Standard)
  • HY-G0010S
    N-desmethyl Netupitant-d6 2070015-21-1 98%
    N-desmethyl Netupitant-d6 is the deuterium labeled N-desmethyl Netupitant, which is a metabolite of Netupitant.
    N-desmethyl Netupitant-d6
  • HY-G0011S
    Netupitant N-oxide-d6 98%
    Netupitant N-oxide-d6 is the deuterium labeled Netupitant N-oxide, which is a metabolite of Netupitant.
    Netupitant N-oxide-d6
  • HY-G0012S
    Monohydroxy Netupitant-d6 98%
    Monohydroxy Netupitant-d6 is the deuterium labeled Monohydroxy Netupitant, which is a metabolite of Netupitant.
    Monohydroxy Netupitant-d6
  • HY-I0021R
    Bepotastine (Standard) 125602-71-3
    Bepotastine (Standard) is the analytical standard of Bepotastine. This product is intended for research and analytical applications. Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research.
    Bepotastine (Standard)
  • HY-I0508R
    Phthalic acid (Standard) 88-99-3
    Phthalic acid (Standard) is the analytical standard of Phthalic acid. This product is intended for research and analytical applications. Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells.
    Phthalic acid (Standard)
  • HY-N0127R
    Yohimbine Hydrochloride (Standard) 65-19-0 98%
    Yohimbine Hydrochloride Standard is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis.
    Yohimbine Hydrochloride (Standard)
  • HY-N0347R
    17α-Hydroxyprogesterone acetate (Standard) 302-23-8
    17α-Hydroxyprogesterone acetate (Standard) is the analytical standard of 17α-Hydroxyprogesterone acetate. This product is intended for research and analytical applications. 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface.
    17α-Hydroxyprogesterone acetate (Standard)
  • HY-N0367S
    Trans-Anethole-d3 444904-67-0 98%
    Trans-Anethole-d3 is deuterated labeled Trans-Anethole (HY-N0367). Trans-Anethole ((E)-Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor.
    Trans-Anethole-d3
  • HY-N0433R
    Astragaloside II (Standard) 84676-89-1
    Astragaloside II (Standard) is the analytical standard of Astragaloside II (HY-N0433). This product is intended for research and analytical applications. Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis.
    Astragaloside II (Standard)
  • HY-N0440R
    Germacrone (Standard) 6902-91-6 98%
    Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 influenza A viruses and the influenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits 5α-reductase and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity.
    Germacrone (Standard)
  • HY-N0470R
    L-Lysine hydrochloride (Standard) 657-27-2
    L-Lysine hydrochloride (Standard) is the analytical standard of L-Lysine hydrochloride. This product is intended for research and analytical applications. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
    L-Lysine hydrochloride (Standard)
  • HY-N0546R
    Ligustroflavone (Standard) 260413-62-5
    Ligustroflavone (Standard) is the analytical standard of Ligustroflavone (HY-N0546). This product is intended for research and analytical applications. Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis.
    Ligustroflavone (Standard)
  • HY-N0607R
    Ginsenoside Ro (Standard) 34367-04-9
    Ginsenoside Ro (Standard) is the analytical standard of Ginsenoside Ro. This product is intended for research and analytical applications. Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca2+-antagonistic antiplatelet effect with an IC50 of 155 μM. Ginsenoside Ro reduces the production of TXA2 more than it reduces the activities of COX-1 and TXAS.
    Ginsenoside Ro (Standard)
  • HY-N0628R
    Kaempferitrin (Standard) 482-38-2
    Kaempferitrin (Standard) is the analytical standard of Kaempferitrin. This product is intended for research and analytical applications. Kaempferitrin is a natural flavonoid, possesses antinociceptive, anti-inflammatory, anti-diabetic, antitumoral and chemopreventive effects, and activates insulin signaling pathway.
    Kaempferitrin (Standard)
  • HY-N0647R
    Silychristin (Standard) 33889-69-9
    Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM.
    Silychristin (Standard)
  • HY-N0687R
    Vindoline (Standard) 2182-14-1 98%
    Vindoline (Standard) is an analytical standard of Vindoline (HY-N0687). This product is intended for research and analytical applications. Vindoline is an orally active vinca alkaloid. Vindoline can be extracted from the leaves of Catharanthus roseus. Vindoline has a weak inhibitory effect on the self-assembly of tubulin. Vindoline alleviates Apoptosis, inhibits p-p65 and p-ERK. Vindoline improves diabetes, bone loss, osteoarthritis, and kidney damage.
    Vindoline (Standard)
  • HY-N12844
    Pseudolaroside B 906482-63-1 98%
    Pseudolaroside B is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi.
    Pseudolaroside B
  • HY-N12845
    Pseudolaroside A 885111-85-3 98%
    Pseudolaroside A is a benzylisoquinoline glycoside that can be isolated from Pseudolarix kaempferi.
    Pseudolaroside A
  • HY-N12853
    6-Methoxynaringenin-7-O-β-D-glucoside 1351949-09-1 98%
    6-Methoxynaringenin-7-O-β-D-glucoside is a methoxynaringenin that can be isolated from Salvia plebeia.
    6-Methoxynaringenin-7-O-β-D-glucoside
Cat. No. Product Name / Synonyms Application Reactivity