1. Endocrinology

Endocrinology

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1392S
    Esmolol-d7 hydrochloride 1346598-13-7
    Esmolol-d7 (hydrochloride) is the deuterium labeled Esmolol hydrochloride. Esmolol hydrochloride is a beta adrenergic receptor blocker[1][2].
    Esmolol-d7 hydrochloride
  • HY-P0236
    Neurokinin A(4-10) 97559-35-8
    Neurokinin A (4-10) is a tachykinin NK2 receptor agonist.
    Neurokinin A(4-10)
  • HY-P0250
    Kassinin 63968-82-1
    Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.
    Kassinin
  • HY-P0255
    Physalaemin 2507-24-6
    Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.
    Physalaemin
  • HY-U00207
    MEN11467 214487-46-4
    MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK1 receptor antagonist.
    MEN11467
  • HY-U00220
    KAT681 373641-87-3
    KAT681 is a liver-selective thyromimetic.
    KAT681
  • HY-U00303
    Trecadrine 90845-56-0
    Trecadrine is a β3-adrenergic agonist.
    Trecadrine
  • HY-101690
    QF0301B 149247-12-1
    QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.
    QF0301B
  • HY-U00104
    YM-46303 171722-81-9
    YM-46303 is an mAChR antagonist which exhibits the highest affinities for M1 and M3 receptors, and selectivity for M3 over M2 receptor.
    YM-46303
  • HY-U00110
    MG 1 148274-76-4
    MG 1 is an α1 adrenergic receptor antagonist.
    MG 1
  • HY-U00168
    KP136 76239-32-2
    KP136 (AL136) is an orally effective antiallergic agent. The IC50 is 76.1 μg/mL for histamine release and 63 ug/mL for degranulation.
    KP136
  • HY-U00170
    Bunaprolast 99107-52-5
    Bunaprolast (U66858) is a potent inhibitor of LTB4 production in human whole blood. Bunaprolast (U66858) also exhibits significant inhibition of lipoxygenase and TXB2 release.
    Bunaprolast
  • HY-U00183
    Epanolol 86880-51-5
    Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
    Epanolol
  • HY-U00188
    A81988 141887-34-5
    A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors.
    A81988
  • HY-U00202
    LY285434 159748-08-0
    LY285434 is a suitable angiotensin II receptor antagonist.
    LY285434
  • HY-U00206
    D2343 72734-63-5
    D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
    D2343
  • HY-U00231
    KF 13218 127654-03-9
    KF 13218 is a potent, selective and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
    KF 13218
  • HY-U00238
    FRG8701 108498-50-6
    FRG-8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.
    FRG8701
  • HY-U00244
    Benzquinamide 63-12-7
    Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively.
    Benzquinamide
  • HY-U00245
    L162441 154512-46-6
    L162441 is an Angiotensin type 1 receptor antagonist.
    L162441
Cat. No. Product Name / Synonyms Application Reactivity