2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W415287
    DL-Thyroxine 300-30-1
    DL-Thyroxine, a thyroid hormone, is a monoamine oxidase inhibitor.
    DL-Thyroxine
  • HY-W436777
    (±)-p-Menthane-3,8-trans-diol 3564-98-5
    (±)-p-Menthane-3,8-trans-diol is a chemosensory compound with inhibitory activity against germination and growth of lettuce (Lactuca satiua L.). (±)-p-Menthane-3,8-trans-diol can be isolated from lemon eucalyptus trees (E. citriodora).
    (±)-p-Menthane-3,8-trans-diol
  • HY-W587916
    (Z)-11-Hexadecenoic acid 2416-20-8
    (Z)-11-Hexadecenoic acid is a sex pheromone capable of attracting male pine processionary moths (Thaumetopoea pityocampa).
    (Z)-11-Hexadecenoic acid
  • HY-W613915
    (±)-Ipsdienol 14434-41-4
    (±)-Ipsdienol is a sex pheromone with an inducing effect on male spruce beetles (Dendroctonus rufipennis Kirby), which can be isolated from the subspecies of spruce beetles (Ips tridens Mannerheim).
    (±)-Ipsdienol
  • HY-W653975
    Bisphenol B-d8 2469735-90-6
    Bisphenol B-d8 is the deuterium labeled Bisphenol B (HY-W013935). Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC). Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models.
    Bisphenol B-d8
  • HY-W673588
    2,3-Dichlorobiphenyl 16605-91-7
    2,3-Dichlorobiphenyl is a polychlorinated biphenyl (PCB). 2,3-Dichlorobiphenyl is an endocrine disruptor that affects gonadal differentiation in Xenopus laevis.
    2,3-Dichlorobiphenyl
  • HY-W674037
    cis-Verbenol 18881-04-4
    cis-Verbenol is a sex pheromone capable of inhibiting aggregation and inducing dispersion of mountain pine beetles (Dendroctonus ponderosae Hopkins) and can be isolated from pine engravers.
    cis-Verbenol
  • HY-W674057
    (Z)-3-Dodecen-1-ol 32451-95-9
    (Z)-3-Dodecen-1-ol is an insect sex pheromone capable of attracting male sweet potato weevils (Cylas formicarius elegantulus).
    (Z)-3-Dodecen-1-ol
  • HY-W701835
    (E,E)-10,12-Hexadecadienal 69977-24-8
    (E,E)-10,12-Hexadecadienal is a female pheromone isolated from female Earias insulana.
    (E,E)-10,12-Hexadecadienal
  • HY-W701984
    11β-Hydroxyetiocholanolone 739-26-4
    11β-Hydroxyetiocholanolone is a metabolite of Hydrocortisone (HY-N0583). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
    11β-Hydroxyetiocholanolone
  • HY-W703425
    17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one 22933-71-7
    17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone), an impurity of Norethindrone, is an anabolic agent. Norethindrone is a progestin athat can be used for endometriosis research.
    17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one
  • HY-W704657
    Monobutyl phosphate-d9 156213-20-6
    Monobutyl phosphate-d9 is the deuterium labeled Monobutyl phosphate (HY-N7143). Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects.
    Monobutyl phosphate-d9
  • HY-W707384
    Candesartan Cilexetil-d11 1261393-19-4
    Candesartan Cilexetil-d11 (TCV-116-d11) is deuterium labeled Candesartan Cilexetil. Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure.
    Candesartan Cilexetil-d11
  • HY-W707517
    Famotidine-d4 2707433-64-3
    Famotidine-d4 (MK-208-d4) is deuterium labeled Famotidine. Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
    Famotidine-d4
  • HY-W710976
    4-Methyl-5-nonanone 35900-26-6
    4-Methyl-5-nonanone is a species-specific sex pheromone isolated from the Asian palm red weevil (Rhynehophorus ferrugineus).
    4-Methyl-5-nonanone
  • HY-W717924
    (Z)-14-Methyl-8-hexadecenal 60609-53-2
    (Z)-14-Methyl-8-hexadecenal is a sex pheromone that can induce mating responses in male Trogoderma beetles, isolated from the spiracular exhalation distillates of female beetles.
    (Z)-14-Methyl-8-hexadecenal
  • HY-W726392
    N-Nitrosometoprolol 138768-62-4
    N-Nitrosometoprolol is an N-nitroso derivative formed by the in vitro reaction of β-adrenergic blockers with sodium nitrite. N-Nitrosometoprolol can induce micronuclei in rat liver, bone marrow and spleen.
    N-Nitrosometoprolol
  • HY-W740216
    N-Demethyl Mifepristone 104004-96-8
    N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone.
    N-Demethyl Mifepristone
  • HY-W741191
    (2E,13Z)-Octadecadienal 99577-57-8
    (2E,13Z)-Octadecadienal is an insect sex pheromone capable of attracting clearwing moths (Synanthedon tipulformis (Clerck)) or raspberry crown borers (Pennisetia marginata (Harris))). (2E,13Z)-Octadecadienal can be isolated from (2E,13Z)-Octadecadienyl acetate, which induces strong responses in male antennae.
    (2E,13Z)-Octadecadienal
  • HY-W741999
    Metaproterenol-d7-1 hemisulfate
    Metaproterenol-d7-1 (hemisulfate) is deuterium labeled Metaproterenol (hemisulfate). Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity.
    Metaproterenol-d7-1 hemisulfate
Cat. No. Product Name / Synonyms Application Reactivity